Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
2R01AI015446-11A3
Application #
2060221
Study Section
Special Emphasis Panel (ZRG5-IMB (02))
Project Start
1988-12-01
Project End
2000-02-29
Budget Start
1996-03-01
Budget End
1997-02-28
Support Year
11
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Northwestern University at Chicago
Department
Microbiology/Immun/Virology
Type
Schools of Dentistry
DUNS #
005436803
City
Chicago
State
IL
Country
United States
Zip Code
60611
Kang, Hee-Kap; Chung, Yun Jo; Park, Chung Ung et al. (2006) Induction of autoimmunity by immunization with hapten-modified hen egg lysozyme in hen egg lysozyme-transgenic mice. Immunology 117:368-78
Kang, H K; Mikszta, J A; Deng, H et al. (2000) Processing and reactivity of T cell epitopes containing two cysteine residues from hen egg-white lysozyme (HEL74-90). J Immunol 164:1775-82
Liu, K J; Schwen, M; Tucker, P W et al. (1998) Hybrid membrane IgM with the transmembrane region of I-A alpha facilitates enhanced presentation of distinct epitopes to T cells. J Immunol 160:4161-8
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Mikszta, J A; Kim, B S (1996) Conversion of low antibody responders into high responders by up-regulating the T cell response to a selective epitope. J Immunol 157:2883-90
Mikszta, J A; Waltenbaugh, C; Kim, B S (1995) Impaired antigen presentation by splenocytes of ethanol-consuming C57BL/6 mice. Alcohol 12:265-71
Jang, Y S; Mikszta, J A; Kim, B S (1994) T cell epitope recognition involved in the low-responsiveness to a region of hen egg lysozyme (46-61) in C57BL/6 mice. Mol Immunol 31:803-12
Liu, K J; Parikh, V S; Tucker, P W et al. (1994) Surface immunoglobulins mediate efficient transport of antigen to lysosomal compartments resulting in enhanced specific antigen presentation by B cells. Eur J Immunol 24:2755-60
Liu, K J; Parikh, V S; Tucker, P W et al. (1993) Role of the B cell antigen receptor in antigen processing and presentation. Involvement of the transmembrane region in intracellular trafficking of receptor/ligand complexes. J Immunol 151:6143-54
Kim, B S; Jang, Y S (1992) Constraints in antigen processing result in unresponsiveness to a T cell epitope of hen egg lysozyme in C57BL/6 mice. Eur J Immunol 22:775-82

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