Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
3R01AI017047-04A2S1
Application #
3126965
Study Section
Bacteriology and Mycology Subcommittee 1 (BM)
Project Start
1980-08-01
Project End
1988-08-31
Budget Start
1985-09-01
Budget End
1986-08-31
Support Year
4
Fiscal Year
1986
Total Cost
Indirect Cost
Name
University of Pittsburgh
Department
Type
Schools of Medicine
DUNS #
053785812
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Dowling, J N; Saha, A K; Glew, R H (1992) Virulence factors of the family Legionellaceae. Microbiol Rev 56:32-60
Saha, A K; Mukhopadhyay, N K; Dowling, J N et al. (1990) Characterization of a phosphomonoesterase from Brucella abortus. Infect Immun 58:1153-8
Holtmann, H; Shemer-Avni, Y; Wessel, K et al. (1990) Inhibition of growth of Chlamydia trachomatis by tumor necrosis factor is accompanied by increased prostaglandin synthesis. Infect Immun 58:3168-72
Pasculle, A W; Veto, G E; Krystofiak, S et al. (1989) Laboratory and clinical evaluation of a commercial DNA probe for the detection of Legionella spp. J Clin Microbiol 27:2350-8
Saha, A K; Dowling, J N; Mukhopadhyay, N K et al. (1989) Legionella micdadei protein kinase catalyzes phosphorylation of tubulin and phosphatidylinositol. J Bacteriol 171:5103-10
Saha, A K; Dowling, J N; Mukhopadhyay, N K et al. (1988) Demonstration of two protein kinases in extracts of Legionella micdadei. J Gen Microbiol 134:1275-81
Saha, A K; Dowling, J N; Pasculle, A W et al. (1988) Legionella micdadei phosphatase catalyzes the hydrolysis of phosphatidylinositol 4,5-bisphosphate in human neutrophils. Arch Biochem Biophys 265:94-104
Levi, M H; Pasculle, A W; Dowling, J N (1987) Role of the alveolar macrophage in host defense and immunity to Legionella micdadei pneumonia in the guinea pig. Microb Pathog 2:269-82
Das, S; Saha, A K; Remaley, A T et al. (1986) Hydrolysis of phosphoproteins and inositol phosphates by cell surface phosphatase of Leishmania donovani. Mol Biochem Parasitol 20:143-53
Dowling, J N; McDevitt, D A; Pasculle, A W (1985) Isolation and preliminary characterization of erythromycin-resistant variants of Legionella micdadei and Legionella pneumophila. Antimicrob Agents Chemother 27:272-4

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