The objective of this research is to evaluate the fungus Lagenidium giganteum as a biocontrol agent for mosquito larvae and to develop practical methods for its use.
Specific aims are: 1) to determine the efficacy and persistence of the fungal mycelia encapsulated in protective media such as alginate, and 2) develop a preliminary simulation model of the epizootiology of the fungus in Culex mosquito-breeding permanent-water pools.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI020886-05
Application #
3130685
Study Section
Tropical Medicine and Parasitology Study Section (TMP)
Project Start
1984-05-01
Project End
1991-01-31
Budget Start
1989-02-01
Budget End
1990-01-31
Support Year
5
Fiscal Year
1989
Total Cost
Indirect Cost
Name
North Carolina State University Raleigh
Department
Type
Earth Sciences/Resources
DUNS #
City
Raleigh
State
NC
Country
United States
Zip Code
27695
Orduz, S; Axtell, R C (1991) Compatibility of Bacillus thuringiensis var. Israelensis and Bacillus sphaericus with the fungal pathogen Lagenidium giganteum (Oomycetes: Lagenidiales). J Am Mosq Control Assoc 7:188-93
Patel, K J; Rueda, L M; Axtell, R C et al. (1991) Temperature-dependent development of the fungal pathogen Lagenidium giganteum (Oomycetes: Lagenidiales) in larvae of Culex quinquefasciatus (Diptera: Culicidae). J Med Entomol 28:95-100
Rueda, L M; Patel, K J; Axtell, R C (1991) Comparison of floating and sinking encapsulated formulations of the fungus Lagenidium giganteum (Oomycetes: Lagenidiales) for control of Anopheles larvae. J Am Mosq Control Assoc 7:250-4
Rueda, L M; Patel, K J; Axtell, R C (1990) Efficacy of encapsulated Lagenidium giganteum (Oomycetes: Lagenidiales) against Culex quinquefasciatus and Aedes aegypti larvae in artificial containers. J Am Mosq Control Assoc 6:694-9
Rueda, L M; Patel, K J; Axtell, R C et al. (1990) Temperature-dependent development and survival rates of Culex quinquefasciatus and Aedes aegypti (Diptera: Culicidae). J Med Entomol 27:892-8
Patel, K J; Rueda, L M; Axtell, R C (1990) Comparisons of different types and concentrations of alginates for encapsulation of Lagenidium giganteum (Oomycetes: Lagenidiales), a fungal pathogen of mosquito larvae. J Am Mosq Control Assoc 6:101-4
Axtell, R C; Guzman, D R (1987) Encapsulation of the mosquito fungal pathogen Lagenidium giganteum (Oomycetes:Lagenidiales) in calcium alginate. J Am Mosq Control Assoc 3:450-9
Guzman, D R; Axtell, R C (1987) Temperature and water quality effects in simulated woodland pools on the infection of Culex mosquito larvae by Lagenidium giganteum (Oomycetes: Lagenidiales) in North Carolina. J Am Mosq Control Assoc 3:211-8
Guzman, D R; Axtell, R C (1987) Population dynamics of Culex quinquefasciatus and the fungal pathogen Lagenidium giganteum (Oomycetes: Lagenidiales) in stagnant water pools. J Am Mosq Control Assoc 3:442-9
Su, X Q; Guzman, D R; Axtell, R C (1986) Factors affecting storage of mycelial cultures of the mosquito fungal pathogen Lagenidium giganteum (Oomycetes: Lagenidiales). J Am Mosq Control Assoc 2:350-4

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