Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI022277-08
Application #
2061770
Study Section
Allergy and Immunology Study Section (ALY)
Project Start
1985-07-01
Project End
1998-05-31
Budget Start
1992-07-01
Budget End
1998-05-31
Support Year
8
Fiscal Year
1992
Total Cost
Indirect Cost

  Institution

Name
University of Texas Sw Medical Center Dallas
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
City
Dallas
State
TX
Country
United States
Zip Code
75390

  Publications

Dinh, T T; McClure, G D; Kennerly, D A (1995) Purification and N-terminal sequence analysis of Streptomyces chromofuscus phospholipase D. Int Arch Allergy Immunol 107:69-71
Chabot, M C; McPhail, L C; Wykle, R L et al. (1992) Comparison of diglyceride production from choline-containing phosphoglycerides in human neutrophils stimulated with N-formylmethionyl-leucylphenylalanine, ionophore A23187 or phorbol 12-myristate 13-acetate. Biochem J 286 ( Pt 3):693-9
Dinh, T T; Kennerly, D A (1991) Assessment of receptor-dependent activation of phosphatidylcholine hydrolysis by both phospholipase D and phospholipase C. Cell Regul 2:299-309
Kennerly, D A (1991) Quantitative analysis of water-soluble products of cell-associated phospholipase C- and phospholipase D-catalyzed hydrolysis of phosphatidylcholine. Methods Enzymol 197:191-7
Murray, J J; Dinh, T T; Truett 3rd, A P et al. (1990) Isolation and enzymic assay of choline and phosphocholine present in cell extracts with picomole sensitivity. Biochem J 270:63-8
Gruchalla, R S; Dinh, T T; Kennerly, D A (1990) An indirect pathway of receptor-mediated 1,2-diacylglycerol formation in mast cells. I. IgE receptor-mediated activation of phospholipase D. J Immunol 144:2334-42
Kennerly, D A (1990) Phosphatidylcholine is a quantitatively more important source of increased 1,2-diacylglycerol than is phosphatidylinositol in mast cells. J Immunol 144:3912-9
Kennerly, D A (1987) Diacylglycerol metabolism in mast cells. Analysis of lipid metabolic pathways using molecular species analysis of intermediates. J Biol Chem 262:16305-13