Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
7R01AI022697-04
Application #
3134183
Study Section
Pathobiochemistry Study Section (PBC)
Project Start
1988-01-01
Project End
1988-11-30
Budget Start
1988-01-01
Budget End
1988-11-30
Support Year
4
Fiscal Year
1987
Total Cost
Indirect Cost
Name
Vanderbilt University Medical Center
Department
Type
Schools of Medicine
DUNS #
004413456
City
Nashville
State
TN
Country
United States
Zip Code
37203
Rinaldo, J E; Clark, M; Parinello, J et al. (1994) Nitric oxide inactivates xanthine dehydrogenase and xanthine oxidase in interferon-gamma-stimulated macrophages. Am J Respir Cell Mol Biol 11:625-30
Shepherd, V L; Cowan, H B; Abdolrasulnia, R et al. (1994) Dexamethasone blocks the interferon-gamma-mediated downregulation of the macrophage mannose receptor. Arch Biochem Biophys 312:367-74
Cowan, H B; Vick, S; Conary, J T et al. (1992) Dexamethasone up-regulates mannose receptor activity by increasing mRNA levels. Arch Biochem Biophys 296:314-20
Shepherd, V L; Tarnowski, B I; McLaughlin, B J (1991) Isolation and characterization of a mannose receptor from human pigment epithelium. Invest Ophthalmol Vis Sci 32:1779-84
Shepherd, V L; Abdolrasulnia, R; Garrett, M et al. (1990) Down-regulation of mannose receptor activity in macrophages after treatment with lipopolysaccharide and phorbol esters. J Immunol 145:1530-6
Shepherd, V L; Abdolrasulnia, R; Stephenson, J et al. (1990) Modulation of mannose receptor activity by proteolysis. Biochem J 270:771-6
Bozeman, P M; Hoidal, J R; Shepherd, V L (1988) Oxidant-mediated inhibition of ligand uptake by the macrophage mannose receptor. J Biol Chem 263:1240-7