Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
7R01AI022726-09
Application #
2061956
Study Section
Tropical Medicine and Parasitology Study Section (TMP)
Project Start
1993-11-01
Project End
1995-02-28
Budget Start
1993-11-01
Budget End
1995-02-28
Support Year
9
Fiscal Year
1993
Total Cost
Indirect Cost
Name
Infectious Disease Research Institute
Department
Type
DUNS #
City
Seattle
State
WA
Country
United States
Zip Code
98102
Skeiky, Y A; Guderian, J A; Benson, D R et al. (1995) A recombinant Leishmania antigen that stimulates human peripheral blood mononuclear cells to express a Th1-type cytokine profile and to produce interleukin 12. J Exp Med 181:1527-37
Skeiky, Y A; Benson, D R; Guderian, J A et al. (1995) Immune responses of leishmaniasis patients to heat shock proteins of Leishmania species and humans. Infect Immun 63:4105-14
Skeiky, Y A; Benson, D R; Elwasila, M et al. (1994) Antigens shared by Leishmania species and Trypanosoma cruzi: immunological comparison of the acidic ribosomal P0 proteins. Infect Immun 62:1643-51
Reed, S G; Brownell, C E; Russo, D M et al. (1994) IL-10 mediates susceptibility to Trypanosoma cruzi infection. J Immunol 153:3135-40
Piuvezam, M R; Russo, D M; Burns Jr, J M et al. (1993) Characterization of responses of normal human T cells to Trypanosoma cruzi antigens. J Immunol 150:916-24
Silva, J S; Barral-Netto, M; Reed, S G (1993) Aggravation of both Trypanosoma cruzi and murine leukemia virus by concomitant infections. Am J Trop Med Hyg 49:589-97
Skeiky, Y A; Benson, D R; Guderian, J A et al. (1993) Trypanosoma cruzi acidic ribosomal P protein gene family. Novel P proteins encoding unusual cross-reactive epitopes. J Immunol 151:5504-15
Arnholdt, A C; Piuvezam, M R; Russo, D M et al. (1993) Analysis and partial epitope mapping of human T cell responses to Trypanosoma cruzi cysteinyl proteinase. J Immunol 151:3171-9
Skeiky, Y A; Benson, D R; Parsons, M et al. (1992) Cloning and expression of Trypanosoma cruzi ribosomal protein P0 and epitope analysis of anti-P0 autoantibodies in Chagas' disease patients. J Exp Med 176:201-11
Silva, J S; Morrissey, P J; Grabstein, K H et al. (1992) Interleukin 10 and interferon gamma regulation of experimental Trypanosoma cruzi infection. J Exp Med 175:169-74

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