Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
7R01AI024138-05
Application #
3136842
Study Section
Allergy and Immunology Study Section (ALY)
Project Start
1988-07-01
Project End
1993-06-30
Budget Start
1992-01-01
Budget End
1992-06-30
Support Year
5
Fiscal Year
1991
Total Cost
Indirect Cost
Name
Monsanto Company
Department
Type
DUNS #
City
St. Louis
State
MO
Country
United States
Zip Code
63141
Fu, X T; Drover, S; Marshall, W H et al. (1995) HLA-DR residues accessible under the peptide-binding groove contribute to polymorphic antibody epitopes. Hum Immunol 43:243-50
Drover, S; Karr, R W; Fu, X T et al. (1994) Analysis of monoclonal antibodies specific for unique and shared determinants on HLA-DR4 molecules. Hum Immunol 40:51-60
Fu, X T; Karr, R W (1994) HLA-DR alpha chain residues located on the outer loops are involved in nonpolymorphic and polymorphic antibody-binding epitopes. Hum Immunol 39:253-60
Klohe, E; Fu, X T; Ballas, M et al. (1993) HLA-DR beta chain residues that are predicted to be located in the floor of the peptide-binding groove contribute to antibody-binding epitopes. Hum Immunol 37:51-8
Fu, X T; Klohe, E; Alber, C et al. (1992) Diverse locations of amino acids in HLA-DR beta chains involved in polymorphic antibody binding epitopes on DR(alpha, beta 1*0101), DR(alpha, beta 1*1101), and DR(alpha,beta 3*0202) molecules. Hum Immunol 33:193-201
Fu, X T; Yu, W Y; Alber, C et al. (1992) Identification of residues involved in polymorphic antibody binding epitopes on HLA-DR molecules. Hum Immunol 33:47-56
Olson, R R; De Magistris, M T; Di Tommaso, A et al. (1992) Mutations in the third, but not the first or second, hypervariable regions of DR(beta 1*0101) eliminate DR1-restricted recognition of a pertussis toxin peptide. J Immunol 148:2703-8
Klohe, E; Pistillo, M P; Ferrara, G B et al. (1992) Critical role of HLA-DR beta 1 residue 58 in multiple polymorphic epitopes recognized by xenogeneic and allogeneic antibodies. Hum Immunol 35:18-28
Hammond, S A; Obah, E; Stanhope, P et al. (1991) Characterization of a conserved T cell epitope in HIV-1 gp41 recognized by vaccine-induced human cytolytic T cells. J Immunol 146:1470-7
Lee, K W; Johnson, A H; Tang, T et al. (1991) DRw11 haplotypes: continuum of DRB1 diversity augmented by unique DQ/DRw52 associations. Hum Immunol 32:150-5

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