Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI024291-09
Application #
2062517
Study Section
AIDS and Related Research Study Section 1 (ARRA)
Project Start
1986-09-30
Project End
1998-03-31
Budget Start
1996-04-01
Budget End
1998-03-31
Support Year
9
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Washington State University
Department
Veterinary Sciences
Type
Schools of Veterinary Medicine
DUNS #
041485301
City
Pullman
State
WA
Country
United States
Zip Code
99164
Mealey, Robert H; Sharif, Amin; Ellis, Shirley A et al. (2005) Early detection of dominant Env-specific and subdominant Gag-specific CD8+ lymphocytes in equine infectious anemia virus-infected horses using major histocompatibility complex class I/peptide tetrameric complexes. Virology 339:110-26
Rivera, Julie A; McGuire, Travis C (2005) Equine infectious anemia virus-infected dendritic cells retain antigen presentation capability. Virology 335:145-54
Chung, Chungwon; Mealey, Robert H; McGuire, Travis C (2005) Evaluation of high functional avidity CTL to Gag epitope clusters in EIAV carrier horses. Virology 342:228-39
Fraser, Darrilyn G; Leib, Steve R; Zhang, Bao Shan et al. (2005) Lymphocyte proliferation responses induced to broadly reactive Th peptides did not protect against equine infectious anemia virus challenge. Clin Diagn Lab Immunol 12:983-93
Chung, Chungwon; Mealey, Robert H; McGuire, Travis C (2004) CTL from EIAV carrier horses with diverse MHC class I alleles recognize epitope clusters in Gag matrix and capsid proteins. Virology 327:144-54
Mealey, Robert H; Leib, Steven R; Pownder, Sarah L et al. (2004) Adaptive immunity is the primary force driving selection of equine infectious anemia virus envelope SU variants during acute infection. J Virol 78:9295-305
McGuire, Travis C; Leib, Steven R; Mealey, Robert H et al. (2003) Presentation and binding affinity of equine infectious anemia virus CTL envelope and matrix protein epitopes by an expressed equine classical MHC class I molecule. J Immunol 171:1984-93
Fraser, Darrilyn G; Mealey, Robert H; McGuire, Travis C (2003) Selecting peptides to optimize Th1 responses to an equine lentivirus using HLA-DR binding motifs and defined HIV-1 Th peptides. Immunogenetics 55:508-14
Mealey, Robert H; Zhang, Baoshan; Leib, Steven R et al. (2003) Epitope specificity is critical for high and moderate avidity cytotoxic T lymphocytes associated with control of viral load and clinical disease in horses with equine infectious anemia virus. Virology 313:537-52
Chung, C; Leib, S R; Fraser, D G et al. (2003) Novel classical MHC class I alleles identified in horses by sequencing clones of reverse transcription-PCR products. Eur J Immunogenet 30:387-96

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