Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI024544-08
Application #
2062625
Study Section
Immunobiology Study Section (IMB)
Project Start
1987-04-01
Project End
1998-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
8
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Jackson Laboratory
Department
Type
DUNS #
042140483
City
Bar Harbor
State
ME
Country
United States
Zip Code
04609
Baker, Pamela J; Howe, Lisa; Garneau, Jessica et al. (2002) T cell knockout mice have diminished alveolar bone loss after oral infection with Porphyromonas gingivalis. FEMS Immunol Med Microbiol 34:45-50
Baker, Pamela J; Roopenian, Derry C (2002) Genetic susceptibility to chronic periodontal disease. Microbes Infect 4:1157-67
Baker, P J; Garneau, J; Howe, L et al. (2001) T-cell contributions to alveolar bone loss in response to oral infection with Porphyromonas gingivalis. Acta Odontol Scand 59:222-5
Baker, P J; DuFour, L; Dixon, M et al. (2000) Adhesion molecule deficiencies increase Porphyromonas gingivalis-induced alveolar bone loss in mice. Infect Immun 68:3103-7
Baker, P J; Dixon, M; Evans, R T et al. (2000) Heterogeneity of Porphyromonas gingivalis strains in the induction of alveolar bone loss in mice. Oral Microbiol Immunol 15:27-32
Baker, P J; Dixon, M; Roopenian, D C (2000) Genetic control of susceptibility to Porphyromonas gingivalis-induced alveolar bone loss in mice. Infect Immun 68:5864-8
Baker, P J (2000) The role of immune responses in bone loss during periodontal disease. Microbes Infect 2:1181-92
Klinge, H; Roopenian, D C (1999) The same genetic regions encode minor histocompatibility antigens detected in the context of different MHC haplotypes. Transplantation 67:1178-83
Baker, P J; Dixon, M; Evans, R T et al. (1999) CD4(+) T cells and the proinflammatory cytokines gamma interferon and interleukin-6 contribute to alveolar bone loss in mice. Infect Immun 67:2804-9
Baker, P J; Carter, S; Dixon, M et al. (1999) Serum antibody response to oral infection precedes but does not prevent Porphyromonas gingivalis-induced alveolar bone loss in mice. Oral Microbiol Immunol 14:194-6

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