Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
3R01AI026450-01S1
Application #
3140195
Study Section
Allergy, Immunology, and Transplantation Research Committee (AITC)
Project Start
1987-09-30
Project End
1992-08-31
Budget Start
1988-07-01
Budget End
1988-08-31
Support Year
1
Fiscal Year
1988
Total Cost
Indirect Cost
Name
Tufts University
Department
Type
DUNS #
City
Boston
State
MA
Country
United States
Zip Code
02111
Rubinstein, D B; Schwartz, R S; Guillaume, T et al. (1994) Germline complexity, restriction fragment length polymorphism, and coding region sequences of the human VH7 gene family identified with family-specific FR3 segment oligonucleotides. Mol Immunol 31:713-21
Stewart, A K; Huang, C; Stollar, B D et al. (1993) High-frequency representation of a single VH gene in the expressed human B cell repertoire. J Exp Med 177:409-18
Rubinstein, D B; Symann, M; Guillaume, T (1993) Oligonucleotide probes to the 5' end of the framework 3 (FR3) gene segment detect polymorphisms of VH gene sequences encoding biologically important amino acid residues. Scand J Immunol 37:33-8
Rubinstein, D B; Symann, M; Stewart, A K et al. (1993) Restriction fragment length polymorphisms and single germline coding region sequence in VH18/2, a duplicated gene encoding autoantibody. Mol Immunol 30:403-12
Sanford, D G; Stollar, B D (1992) Assay of anti-DNA antibodies. Methods Enzymol 212:355-71
Huang, C; Stewart, A K; Schwartz, R S et al. (1992) Immunoglobulin heavy chain gene expression in peripheral blood B lymphocytes. J Clin Invest 89:1331-43
Stewart, A K; Huang, C; Long, A A et al. (1992) VH-gene representation in autoantibodies reflects the normal human B-cell repertoire. Immunol Rev 128:101-22
Stollar, B D (1991) Autoantibodies and autoantigens: a conserved system that may shape a primary immunoglobulin gene pool. Mol Immunol 28:1399-412
Stollar, B D (1990) The biochemistry and genetics of DNA and anti-DNA antibodies. Clin Rheumatol 9:30-8
Sabbaga, J; Pankewycz, O G; Lufft, V et al. (1990) Cross-reactivity distinguishes serum and nephritogenic anti-DNA antibodies in human lupus from their natural counterparts in normal serum. J Autoimmun 3:215-35

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