Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI027771-15
Application #
2064087
Study Section
Immunological Sciences Study Section (IMS)
Project Start
1988-08-01
Project End
1998-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
15
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of Louisville
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
City
Louisville
State
KY
Country
United States
Zip Code
40292

  Publications

Yan, J; Vetvicka, V; Xia, Y et al. (2000) Critical role of Kupffer cell CR3 (CD11b/CD18) in the clearance of IgM-opsonized erythrocytes or soluble beta-glucan. Immunopharmacology 46:39-54
Vyytvicka, V; Hanikyrova, M; Vyytvickova, J et al. (1999) Regulation of CR3 (CD11b/CD18)-dependent natural killer (NK) cell cytotoxicity by tumour target cell MHC class I molecules. Clin Exp Immunol 115:229-35
Yan, J; Vetvicka, V; Xia, Y et al. (1999) Beta-glucan, a ""specific"" biologic response modifier that uses antibodies to target tumors for cytotoxic recognition by leukocyte complement receptor type 3 (CD11b/CD18). J Immunol 163:3045-52
Xia, Y; Vetvicka, V; Yan, J et al. (1999) The beta-glucan-binding lectin site of mouse CR3 (CD11b/CD18) and its function in generating a primed state of the receptor that mediates cytotoxic activation in response to iC3b-opsonized target cells. J Immunol 162:2281-90
Xia, Y; Ross, G D (1999) Generation of recombinant fragments of CD11b expressing the functional beta-glucan-binding lectin site of CR3 (CD11b/CD18). J Immunol 162:7285-93
Reddy, R K; Xia, Y; Hanikyrova, M et al. (1998) A mixed population of immature and mature leucocytes in umbilical cord blood results in a reduced expression and function of CR3 (CD11b/CD18). Clin Exp Immunol 114:462-7
Vetvicka, V; Thornton, B P; Wieman, T J et al. (1997) Targeting of natural killer cells to mammary carcinoma via naturally occurring tumor cell-bound iC3b and beta-glucan-primed CR3 (CD11b/CD18). J Immunol 159:599-605
Thornton, B P; Vyytvicka, V; Pitman, M et al. (1996) Analysis of the sugar specificity and molecular location of the beta-glucan-binding lectin site of complement receptor type 3 (CD11b/CD18). J Immunol 156:1235-46
Pryzwansky, K B (1994) High voltage immunoelectron microscopy of complement receptor type 3-mediated capping and internalization of group A streptococcal cell walls by human neutrophils. Microsc Res Tech 28:263-76
Vyytvicka, V; Vyyktvickova, J; Fusek, M (1994) Effect of human procathepsin D on proliferation of human cell lines. Cancer Lett 79:131-5

Showing the most recent 10 out of 15 publications