Regulation of Human Ige Synthesis by Cytokines

Buckley, Rebecca H.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Allergy and Infectious Diseases (NIAID)
• Type: Research Project (R01)
• Project #: 5R01AI028414-07
• Application #: 2064444
• Study Section: Immunological Sciences Study Section (IMS)
• Project Start: 1989-09-30
• Project End: 1998-03-31
• Budget Start: 1996-04-01
• Budget End: 1997-03-31
• Support Year: 7
• Fiscal Year: 1996

Institution

• Name: Duke University
• Department: Pediatrics
• Type: Schools of Medicine
• DUNS #: 071723621
• City: Durham
• State: NC
• Country: United States
• Zip Code: 27705

Publications

Claassen, J L; Levine, A D; Buckley, R H (1992) Mechanism of pokeweed mitogen inhibition of rhIL-4-induced human IgE synthesis. Cell Immunol 140:357-69

Claasen, J J; Levine, A D; Schiff, S E et al. (1991) Mononuclear cells from patients with the hyper-IgE syndrome produce little IgE when they are stimulated with recombinant human interleukin-4. J Allergy Clin Immunol 88:713-21

Sheerin, K A; Buckley, R H (1991) Antibody responses to protein, polysaccharide, and phi X174 antigens in the hyperimmunoglobulinemia E (hyper-IgE) syndrome. J Allergy Clin Immunol 87:803-11

Claassen, J L; Levine, A D; Buckley, R H (1990) Recombinant human IL-4 induces IgE and IgG synthesis by normal and atopic donor mononuclear cells. Similar dose response, time course, requirement for T cells, and effect of pokeweed mitogen. J Immunol 144:2123-30

Claassen, J L; Levine, A D; Buckley, R H (1990) A cell culture system that enhances mononuclear cell IgE synthesis induced by recombinant human interleukin-4. J Immunol Methods 126:213-22