Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI029544-07
Application #
2065047
Study Section
Immunobiology Study Section (IMB)
Project Start
1991-01-01
Project End
1998-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
7
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Oregon Health and Science University
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
009584210
City
Portland
State
OR
Country
United States
Zip Code
97239
Koguchi, Yoshinobu; Thauland, Timothy J; Slifka, Mark K et al. (2007) Preformed CD40 ligand exists in secretory lysosomes in effector and memory CD4+ T cells and is quickly expressed on the cell surface in an antigen-specific manner. Blood 110:2520-7
Wetzel, Scott A; Parker, David C (2006) MHC transfer from APC to T cells following antigen recognition. Crit Rev Immunol 26:1-21
Dullforce, Per A; Seitz, Greg W; Garman, Kiera L et al. (2006) Antigen-specific accumulation of naive, memory and effector CD4 T cells during anterior uveitis monitored by intravital microscopy. Cell Immunol 239:49-60
Wetzel, Scott A; McKeithan, Timothy W; Parker, David C (2005) Peptide-specific intercellular transfer of MHC class II to CD4+ T cells directly from the immunological synapse upon cellular dissociation. J Immunol 174:80-9
Wetzel, Scott A; McKeithan, Timothy W; Parker, David C (2002) Live-cell dynamics and the role of costimulation in immunological synapse formation. J Immunol 169:6092-101
Evans, D E; Munks, M W; Purkerson, J M et al. (2000) Resting B lymphocytes as APC for naive T lymphocytes: dependence on CD40 ligand/CD40. J Immunol 164:688-97
Baird, A M; Parker, D C (1996) Analysis of low zone tolerance induction in normal and B cell-deficient mice. J Immunol 157:1833-9
Yuschenkoff, V N; Sethna, M P; Freeman, G J et al. (1996) Coexpression of B7-1 and antigen blocks tolerance induction to antigen presented by resting B cells. J Immunol 157:1987-95
Lalmanach-Girard, A C; Chiles, T C; Parker, D C et al. (1993) T cell-dependent induction of NF-kappa B in B cells. J Exp Med 177:1215-9
Eynon, E E; Parker, D C (1993) Parameters of tolerance induction by antigen targeted to B lymphocytes. J Immunol 151:2958-64

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