Efflux-Mediated Resistance to Tetracyclines

Levy, Stuart B.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Allergy and Infectious Diseases (NIAID)
• Type: Research Project (R01)
• Project #: 5R01AI030646-05
• Application #: 2065816
• Study Section: Bacteriology and Mycology Subcommittee 2 (BM)
• Project Start: 1991-01-01
• Project End: 1996-12-31
• Budget Start: 1995-01-01
• Budget End: 1996-12-31
• Support Year: 5
• Fiscal Year: 1995

Institution

• Name: Tufts University
• Department: Biochemistry
• Type: Schools of Medicine
• DUNS #: 604483045
• City: Boston
• State: MA
• Country: United States
• Zip Code: 02111

Publications

Aldema, M L; McMurry, L M; Walmsley, A R et al. (1996) Purification of the Tn10-specified tetracycline efflux antiporter TetA in a native state as a polyhistidine fusion protein. Mol Microbiol 19:187-95

McMurry, L M; Levy, S B (1995) The NH2-terminal half of the Tn10-specified tetracycline efflux protein TetA contains a dimerization domain. J Biol Chem 270:22752-7

Rubin, R A; Levy, S B (1991) Tet protein domains interact productively to mediate tetracycline resistance when present on separate polypeptides. J Bacteriol 173:4503-9