Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI030917-06
Application #
2065981
Study Section
AIDS and Related Research Study Section 4 (ARRD)
Project Start
1991-03-01
Project End
1997-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Maryland Baltimore
Department
Chemistry
Type
Schools of Medicine
DUNS #
003255213
City
Baltimore
State
MD
Country
United States
Zip Code
21201
Mercredi, Peter Y; Bucca, Nadine; Loeliger, Burk et al. (2016) Structural and Molecular Determinants of Membrane Binding by the HIV-1 Matrix Protein. J Mol Biol 428:1637-55
Tedbury, Philip R; Mercredi, Peter Y; Gaines, Christy R et al. (2015) Elucidating the mechanism by which compensatory mutations rescue an HIV-1 matrix mutant defective for gag membrane targeting and envelope glycoprotein incorporation. J Mol Biol 427:1413-1427
Zhang, Hongtao; Curreli, Francesca; Waheed, Abdul A et al. (2013) Dual-acting stapled peptides target both HIV-1 entry and assembly. Retrovirology 10:136
Checkley, Mary Ann; Luttge, Benjamin G; Mercredi, Peter Y et al. (2013) Reevaluation of the requirement for TIP47 in human immunodeficiency virus type 1 envelope glycoprotein incorporation. J Virol 87:3561-70
Kyere, Sampson K; Mercredi, Peter Y; Dong, Xinhong et al. (2012) The HIV-1 matrix protein does not interact directly with the protein interactive domain of AP-3?. Virus Res 169:411-4
Lu, Kun; Heng, Xiao; Summers, Michael F (2011) Structural determinants and mechanism of HIV-1 genome packaging. J Mol Biol 410:609-33
Summers, Michael F (2011) Training the next generation of protein scientists. Protein Sci 20:1796-801
Hamard-Peron, E; Juillard, F; Saad, J S et al. (2010) Targeting of murine leukemia virus gag to the plasma membrane is mediated by PI(4,5)P2/PS and a polybasic region in the matrix. J Virol 84:503-15
Valentine, Kathleen G; Peterson, Ronald W; Saad, Jamil S et al. (2010) Reverse micelle encapsulation of membrane-anchored proteins for solution NMR studies. Structure 18:9-16
Kyere, Sampson K; Joseph, Prem Raj B; Summers, Michael F (2008) The p12 domain is unstructured in a murine leukemia virus p12-CA(N) Gag construct. PLoS One 3:e1902

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