Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
2R01AI031343-04A1
Application #
2066308
Study Section
AIDS and Related Research Study Section 4 (ARRD)
Project Start
1992-01-01
Project End
1999-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
New York University
Department
Biochemistry
Type
Schools of Medicine
DUNS #
City
New York
State
NY
Country
United States
Zip Code
10016

  Publications

Lee-Huang, Sylvia; Huang, Philip Lin; Huang, Paul Lee (2014) Live-cell real-time imaging of mitochondria in HIV-1-infected cells. AIDS Res Hum Retroviruses 30:1025-6
Li, Hui-Guang; Huang, Philip L; Zhang, Dawei et al. (2010) A new activity of anti-HIV and anti-tumor protein GAP31: DNA adenosine glycosidase--structural and modeling insight into its functions. Biochem Biophys Res Commun 391:340-5
Lee-Huang, Sylvia; Maiorov, Vladimir; Huang, Philip L et al. (2005) Structural and functional modeling of human lysozyme reveals a unique nonapeptide, HL9, with anti-HIV activity. Biochemistry 44:4648-55
Lee-Huang, S; Huang, P L; Sun, Y et al. (2000) Inhibition of MDA-MB-231 human breast tumor xenografts and HER2 expression by anti-tumor agents GAP31 and MAP30. Anticancer Res 20:653-9
Wang, Y X; Jacob, J; Wingfield, P T et al. (2000) Anti-HIV and anti-tumor protein MAP30, a 30 kDa single-strand type-I RIP, shares similar secondary structure and beta-sheet topology with the A chain of ricin, a type-II RIP. Protein Sci 9:138-44
Wang, Y X; Neamati, N; Jacob, J et al. (1999) Solution structure of anti-HIV-1 and anti-tumor protein MAP30: structural insights into its multiple functions. Cell 99:433-42
Schreiber, C A; Wan, L; Sun, Y et al. (1999) The antiviral agents, MAP30 and GAP31, are not toxic to human spermatozoa and may be useful in preventing the sexual transmission of human immunodeficiency virus type 1. Fertil Steril 72:686-90
Huang, P L; Sun, Y; Chen, H C et al. (1999) Proteolytic fragments of anti-HIV and anti-tumor proteins MAP30 and GAP31 are biologically active. Biochem Biophys Res Commun 262:615-23
Bourinbaiar, A S; Lee-Huang, S (1996) The activity of plant-derived antiretroviral proteins MAP30 and GAP31 against herpes simplex virus in vitro. Biochem Biophys Res Commun 219:923-9
Bourinbaiar, A S; Lee-Huang, S (1995) Acrosin inhibitor, 4'-acetamidophenyl 4-guanidinobenzoate, an experimental vaginal contraceptive with anti-HIV activity. Contraception 51:319-22

Showing the most recent 10 out of 18 publications