Immunity Against Opportunistic Cryptococcus Neoformans

Hill, Joseph O.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Allergy and Infectious Diseases (NIAID)
• Type: Research Project (R01)
• Project #: 3R01AI031344-03S1
• Application #: 3146318
• Study Section: AIDS and Related Research Study Section 5 (ARRE)
• Project Start: 1993-03-01
• Project End: 1995-02-28
• Budget Start: 1993-03-01
• Budget End: 1994-02-28
• Support Year: 3
• Fiscal Year: 1993

Institution

• Name: Trudeau Institute, Inc.
• City: Saranac Lake
• State: NY
• Country: United States
• Zip Code: 12983

Publications

Aguirre, K M; Sayles, P C; Gibson, G W et al. (1996) Resistance to Cryptococcus neoformans is associated with an inflammatory response to Toxoplasma gondii in the central nervous system of mice. Infect Immun 64:77-82

Aguirre, K; Havell, E A; Gibson, G W et al. (1995) Role of tumor necrosis factor and gamma interferon in acquired resistance to Cryptococcus neoformans in the central nervous system of mice. Infect Immun 63:1725-31

Hill, J O; Aguirre, K M (1994) CD4+ T cell-dependent acquired state of immunity that protects the brain against Cryptococcus neoformans. J Immunol 152:2344-50

Hill, J O; Dunn, P L (1993) A T cell-independent protective host response against Cryptococcus neoformans expressed at the primary site of infection in the lung. Infect Immun 61:5302-8

Hill, J O (1992) CD4+ T cells cause multinucleated giant cells to form around Cryptococcus neoformans and confine the yeast within the primary site of infection in the respiratory tract. J Exp Med 175:1685-95