Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
2R01AI032319-05
Application #
2067192
Study Section
AIDS and Related Research Study Section 4 (ARRD)
Project Start
1991-09-30
Project End
2000-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Rochester
Department
Obstetrics & Gynecology
Type
Schools of Dentistry
DUNS #
208469486
City
Rochester
State
NY
Country
United States
Zip Code
14627
Polliotti, B M; Gnall-Sazenski, S; Laughlin, T S et al. (2002) Inhibitory effects of human chorionic gonadotropin (hCG) preparations on HIV infection of human placenta in vitro. Placenta 23 Suppl A:S102-6
Sheikh, A U; Polliotti, B M; Miller, R K (2000) Human immunodeficiency virus infection: in situ polymerase chain reaction localization in human placentas after in utero and in vitro infection. Am J Obstet Gynecol 182:207-13
Sheikh, A U; Polliotti, B M; Miller, R K (2000) In situ PCR detection of HIV expression in the human placenta. Methods Mol Biol 137:75-86
Miller, R K; Polliotti, B M; Laughlin, T et al. (2000) Role of the placenta in fetal HIV infection. Teratology 61:391-4
Plessinger, M A; Miller, R K (1999) Effects of zidovudine (AZT) and dideoxyinosine (ddI) on human trophoblast cells. Reprod Toxicol 13:537-46
Boal, J H; Plessinger, M A; van den Reydt, C et al. (1997) Pharmacokinetic and toxicity studies of AZT (zidovudine) following perfusion of human term placenta for 14 hours. Toxicol Appl Pharmacol 143:13-21
Plessinger, M A; Boal, J H; Miller, R K (1997) Human placenta does not Reduce AZT (zidovudine) to 3'-amino-3'-deoxythymidine. Proc Soc Exp Biol Med 215:243-7
Genbacev, O; White, T E; Gavin, C E et al. (1993) Human trophoblast cultures: models for implantation and peri-implantation toxicology. Reprod Toxicol 7 Suppl 1:75-94