Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI032433-05
Application #
2067323
Study Section
Special Emphasis Panel (ZRG5-ARRB (02))
Project Start
1992-05-01
Project End
1999-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Allegheny University of Health Sciences
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
City
Philadelphia
State
PA
Country
United States
Zip Code
19129
Edlind, T D; Henry, K W; Metera, K A et al. (2001) Aspergillus fumigatus CYP51 sequence: potential basis for fluconazole resistance. Med Mycol 39:299-302
Katiyar, S K; Edlind, T D (2001) Identification and expression of multidrug resistance-related ABC transporter genes in Candida krusei. Med Mycol 39:109-16
Henry, K W; Nickels, J T; Edlind, T D (2000) Upregulation of ERG genes in Candida species by azoles and other sterol biosynthesis inhibitors. Antimicrob Agents Chemother 44:2693-700
Henry, K W; Cruz, M C; Katiyar, S K et al. (1999) Antagonism of azole activity against Candida albicans following induction of multidrug resistance genes by selected antimicrobial agents. Antimicrob Agents Chemother 43:1968-74
Katiyar, S K; Edlind, T D (1997) In vitro susceptibilities of the AIDS-associated microsporidian Encephalitozoon intestinalis to albendazole, its sulfoxide metabolite, and 12 additional benzimidazole derivatives. Antimicrob Agents Chemother 41:2729-32
Cruz, M C; Edlind, T (1997) beta-Tubulin genes and the basis for benzimidazole sensitivity of the opportunistic fungus Cryptococcus neoformans. Microbiology 143 ( Pt 6):2003-8
Edlind, T; Katiyar, S; Visvesvara, G et al. (1996) Evolutionary origins of Microsporidia and basis for benzimidazole sensitivity: an update. J Eukaryot Microbiol 43:109S
Edlind, T D; Li, J; Visvesvara, G S et al. (1996) Phylogenetic analysis of beta-tubulin sequences from amitochondrial protozoa. Mol Phylogenet Evol 5:359-67
Li, J; Katiyar, S K; Edlind, T D (1996) Site-directed mutagenesis of Saccharomyces cerevisiae beta-tubulin: interaction between residue 167 and benzimidazole compounds. FEBS Lett 385:7-10
Katiyar, S K; Edlind, T D (1996) Entamoeba histolytica encodes a highly divergent beta-tubulin. J Eukaryot Microbiol 43:31-4

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