Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI032486-05
Application #
2067379
Study Section
AIDS and Related Research Study Section 3 (ARRC)
Project Start
1992-02-01
Project End
1997-01-31
Budget Start
1996-02-01
Budget End
1997-01-31
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Massachusetts Institute of Technology
Department
Type
Organized Research Units
DUNS #
City
Cambridge
State
MA
Country
United States
Zip Code
02139
Stewart, Sheila A; Dykxhoorn, Derek M; Palliser, Deborah et al. (2003) Lentivirus-delivered stable gene silencing by RNAi in primary cells. RNA 9:493-501
Ge, Qing; McManus, Michael T; Nguyen, Tam et al. (2003) RNA interference of influenza virus production by directly targeting mRNA for degradation and indirectly inhibiting all viral RNA transcription. Proc Natl Acad Sci U S A 100:2718-23
Lee, Keng-Boon; Wang, Dong; Lippard, Stephen J et al. (2002) Transcription-coupled and DNA damage-dependent ubiquitination of RNA polymerase II in vitro. Proc Natl Acad Sci U S A 99:4239-44
Kim, J B; Sharp, P A (2001) Positive transcription elongation factor B phosphorylates hSPT5 and RNA polymerase II carboxyl-terminal domain independently of cyclin-dependent kinase-activating kinase. J Biol Chem 276:12317-23
Tuschl, T; Sharp, P A; Bartel, D P (2001) A ribozyme selected from variants of U6 snRNA promotes 2',5'-branch formation. RNA 7:29-43
Blencowe, B J; Bauren, G; Eldridge, A G et al. (2000) The SRm160/300 splicing coactivator subunits. RNA 6:111-20
Gilbert, S L; Sharp, P A (1999) Promoter-specific hypoacetylation of X-inactivated genes. Proc Natl Acad Sci U S A 96:13825-30
Mitsui, A; Sharp, P A (1999) Ubiquitination of RNA polymerase II large subunit signaled by phosphorylation of carboxyl-terminal domain. Proc Natl Acad Sci U S A 96:6054-9
Page-McCaw, P S; Amonlirdviman, K; Sharp, P A (1999) PUF60: a novel U2AF65-related splicing activity. RNA 5:1548-60
Kim, J B; Yamaguchi, Y; Wada, T et al. (1999) Tat-SF1 protein associates with RAP30 and human SPT5 proteins. Mol Cell Biol 19:5960-8

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