Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
2R01AI032489-06
Application #
2067383
Study Section
Molecular Biology Study Section (MBY)
Project Start
1991-08-01
Project End
2001-05-31
Budget Start
1996-06-01
Budget End
1997-05-31
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Rockefeller University
Department
Anatomy/Cell Biology
Type
Other Domestic Higher Education
DUNS #
071037113
City
New York
State
NY
Country
United States
Zip Code
10065
Ahmed, Simi T; Darnell Jr, James E (2009) Serpin B3/B4, activated by STAT3, promote survival of squamous carcinoma cells. Biochem Biophys Res Commun 378:821-5
Betz, Aurel; Ryoo, Hyung Don; Steller, Hermann et al. (2008) STAT92E is a positive regulator of Drosophila inhibitor of apoptosis 1 (DIAP/1) and protects against radiation-induced apoptosis. Proc Natl Acad Sci U S A 105:13805-10
Ginsberg, Michael; Czeko, Elmar; Muller, Patrick et al. (2007) Amino acid residues required for physical and cooperative transcriptional interaction of STAT3 and AP-1 proteins c-Jun and c-Fos. Mol Cell Biol 27:6300-8
Mertens, Claudia; Zhong, Minghao; Krishnaraj, Ravi et al. (2006) Dephosphorylation of phosphotyrosine on STAT1 dimers requires extensive spatial reorientation of the monomers facilitated by the N-terminal domain. Genes Dev 20:3372-81
Shen, Yuhong; La Perle, Krista M D; Levy, David E et al. (2005) Reduced STAT3 activity in mice mimics clinical disease syndromes. Biochem Biophys Res Commun 330:305-9
Paz, Keren; Socci, Nicholas D; van Nimwegen, Erik et al. (2004) Transformation fingerprint: induced STAT3-C, v-Src and Ha-Ras cause small initial changes but similar established profiles in mRNA. Oncogene 23:8455-63
Shen, Yuhong; Schlessinger, Karni; Zhu, Xuejun et al. (2004) Essential role of STAT3 in postnatal survival and growth revealed by mice lacking STAT3 serine 727 phosphorylation. Mol Cell Biol 24:407-19
Yang, Edward; Lerner, Lorena; Besser, Daniel et al. (2003) Independent and cooperative activation of chromosomal c-fos promoter by STAT3. J Biol Chem 278:15794-9
Yang, Edward; van Nimwegen, Erik; Zavolan, Mihaela et al. (2003) Decay rates of human mRNAs: correlation with functional characteristics and sequence attributes. Genome Res 13:1863-72
Lerner, Lorena; Henriksen, Melissa A; Zhang, Xiaokui et al. (2003) STAT3-dependent enhanceosome assembly and disassembly: synergy with GR for full transcriptional increase of the alpha 2-macroglobulin gene. Genes Dev 17:2564-77

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