Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI033492-02
Application #
2068520
Study Section
Tropical Medicine and Parasitology Study Section (TMP)
Project Start
1995-09-15
Project End
1999-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Harvard University
Department
Microbiology/Immun/Virology
Type
Schools of Public Health
DUNS #
082359691
City
Boston
State
MA
Country
United States
Zip Code
02115
Nixon, Julie E J; Field, Jessica; McArthur, Andrew G et al. (2003) Iron-dependent hydrogenases of Entamoeba histolytica and Giardia lamblia: activity of the recombinant entamoebic enzyme and evidence for lateral gene transfer. Biol Bull 204:1-9
Van Dellen, Katrina; Ghosh, Sudip K; Robbins, Phillips W et al. (2002) Entamoeba histolytica lectins contain unique 6-Cys or 8-Cys chitin-binding domains. Infect Immun 70:3259-63
Van Dellen, Katrina; Field, Jessica; Wang, Zheng et al. (2002) LINEs and SINE-like elements of the protist Entamoeba histolytica. Gene 297:229-39
Nixon, Julie E J; Wang, Amy; Field, Jessica et al. (2002) Evidence for lateral transfer of genes encoding ferredoxins, nitroreductases, NADH oxidase, and alcohol dehydrogenase 3 from anaerobic prokaryotes to Giardia lamblia and Entamoeba histolytica. Eukaryot Cell 1:181-90
Nixon, Julie E J; Wang, Amy; Morrison, Hilary G et al. (2002) A spliceosomal intron in Giardia lamblia. Proc Natl Acad Sci U S A 99:3701-5
Ghosh, S; Frisardi, M; Rogers, R et al. (2001) How Giardia swim and divide. Infect Immun 69:7866-72
Ghosh, S K; Rosenthal, B; Rogers, R et al. (2000) Vacuolar localization of an Entamoeba histolytica homologue of the plasma membrane ATPase (PMCA). Mol Biochem Parasitol 108:125-30
Field, J; Wilson, M P; Mai, Z et al. (2000) An Entamoeba histolytica inositol 1,3,4-trisphosphate 5/6-kinase has a novel 3-kinase activity. Mol Biochem Parasitol 108:119-23
Frisardi, M; Ghosh, S K; Field, J et al. (2000) The most abundant glycoprotein of amebic cyst walls (Jacob) is a lectin with five Cys-rich, chitin-binding domains. Infect Immun 68:4217-24
Ghosh, S; Frisardi, M; Ramirez-Avila, L et al. (2000) Molecular epidemiology of Entamoeba spp.: evidence of a bottleneck (Demographic sweep) and transcontinental spread of diploid parasites. J Clin Microbiol 38:3815-21

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