Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI033532-02
Application #
2068586
Study Section
Medical Biochemistry Study Section (MEDB)
Project Start
1995-07-01
Project End
1998-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Nebraska Medical Center
Department
Pathology
Type
Schools of Medicine
DUNS #
City
Omaha
State
NE
Country
United States
Zip Code
68198
Erdos, Melinda; Uzvolgyi, Eva; Nemes, Zoltan et al. (2005) Characterization of a new disease-causing mutation of SH2D1A in a family with X-linked lymphoproliferative disease. Hum Mutat 25:506
Yin, Luo; Al-Alem, Umaima; Liang, Jun et al. (2003) Mice deficient in the X-linked lymphoproliferative disease gene sap exhibit increased susceptibility to murine gammaherpesvirus-68 and hypo-gammaglobulinemia. J Med Virol 71:446-55
Sumegi, Janos; Seemayer, Thomas A; Huang, Dali et al. (2002) A spectrum of mutations in SH2D1A that causes X-linked lymphoproliferative disease and other Epstein-Barr virus-associated illnesses. Leuk Lymphoma 43:1189-201
Sumegi, J; Huang, D; Lanyi, A et al. (2000) Correlation of mutations of the SH2D1A gene and epstein-barr virus infection with clinical phenotype and outcome in X-linked lymphoproliferative disease. Blood 96:3118-25
Nagy, N; Cerboni, C; Mattsson, K et al. (2000) SH2D1A and SLAM protein expression in human lymphocytes and derived cell lines. Int J Cancer 88:439-47
Sumegi, J; Gross, T G; Seemayer, T A (1999) The molecular genetics of X-linked lymphoproliferative (Duncan's) disease. Cancer J Sci Am 5:57-62
Coffey, A J; Brooksbank, R A; Brandau, O et al. (1998) Host response to EBV infection in X-linked lymphoproliferative disease results from mutations in an SH2-domain encoding gene. Nat Genet 20:129-35
Bolino, A; Yin, L; Seri, M et al. (1998) A new candidate region for the positional cloning of the XLP gene. Eur J Hum Genet 6:509-17
Lanyi, A; Li, B; Li, S et al. (1997) A yeast artificial chromosome (YAC) contig encompassing the critical region of the X-linked lymphoproliferative disease (XLP) locus. Genomics 39:55-65