Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
2R01AI033679-04A1
Application #
2068730
Study Section
Immunobiology Study Section (IMB)
Project Start
1993-01-01
Project End
1997-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Dana-Farber Cancer Institute
Department
Type
DUNS #
149617367
City
Boston
State
MA
Country
United States
Zip Code
02215
Razi-Wolf, Z; Hollander, G A; Reiser, H (1996) Activation of CD4+ T lymphocytes form interleukin 2-deficient mice by costimulatory B7 molecules. Proc Natl Acad Sci U S A 93:2903-8
Reiser, H; Stadecker, M J (1996) Costimulatory B7 molecules in the pathogenesis of infectious and autoimmune diseases. N Engl J Med 335:1369-77
Reiser, H; Schneeberger, E E (1996) Expression and function of B7-1 and B7-2 in hapten-induced contact sensitivity. Eur J Immunol 26:880-5
Wetzler, L M; Ho, Y; Reiser, H et al. (1996) Neisserial porins induce B lymphocytes to express costimulatory B7-2 molecules and to proliferate. J Exp Med 183:1151-9
Natesan, M; Razi-Wolf, Z; Reiser, H (1996) Costimulation of IL-4 production by murine B7-1 and B7-2 molecules. J Immunol 156:2783-91
Flores Villanueva, P O; Reiser, H; Stadecker, M J (1994) Regulation of T helper cell responses in experimental murine schistosomiasis by IL-10. Effect on expression of B7 and B7-2 costimulatory molecules by macrophages. J Immunol 153:5190-9
Reiser, H; Schneeberger, E E (1994) The costimulatory molecule B7 is expressed in the medullary region of the murine thymus. Immunology 81:532-7
Razi-Wolf, Z; Falo Jr, L D; Reiser, H (1994) Expression and function of the costimulatory molecule B7 on murine Langerhans cells: evidence for an alternative CTLA-4 ligand. Eur J Immunol 24:805-11
Razi-Wolf, Z; Galvin, F; Gray, G et al. (1993) Evidence for an additional ligand, distinct from B7, for the CTLA-4 receptor. Proc Natl Acad Sci U S A 90:11182-6
Freeman, G J; Borriello, F; Hodes, R J et al. (1993) Murine B7-2, an alternative CTLA4 counter-receptor that costimulates T cell proliferation and interleukin 2 production. J Exp Med 178:2185-92