Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI034757-03
Application #
2069913
Study Section
Special Emphasis Panel (SRC (82))
Project Start
1993-11-01
Project End
1997-10-31
Budget Start
1995-11-01
Budget End
1996-10-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Children's Hospital Boston
Department
Type
DUNS #
076593722
City
Boston
State
MA
Country
United States
Zip Code
02115
Mantis, Nicholas J; Palaia, Jana; Hessell, Ann J et al. (2007) Inhibition of HIV-1 infectivity and epithelial cell transfer by human monoclonal IgG and IgA antibodies carrying the b12 V region. J Immunol 179:3144-52
Kozlowski, Pamela A; Neutra, Marian R (2003) The role of mucosal immunity in prevention of HIV transmission. Curr Mol Med 3:217-28
Shreedhar, Vijay K; Kelsall, Brian L; Neutra, Marian R (2003) Cholera toxin induces migration of dendritic cells from the subepithelial dome region to T- and B-cell areas of Peyer's patches. Infect Immun 71:504-9
Kozlowski, Pamela A; Williams, Selvi B; Lynch, Rebecca M et al. (2002) Differential induction of mucosal and systemic antibody responses in women after nasal, rectal, or vaginal immunization: influence of the menstrual cycle. J Immunol 169:566-74
Didierlaurent, Arnaud; Sirard, Jean-Claude; Kraehenbuhl, Jean-Pierre et al. (2002) How the gut senses its content. Cell Microbiol 4:61-72
Mantis, Nicholas J; Cheung, Marsha C; Chintalacharuvu, Koteswara R et al. (2002) Selective adherence of IgA to murine Peyer's patch M cells: evidence for a novel IgA receptor. J Immunol 169:1844-51
Mantis, N J; Kozlowski, P A; Mielcarz, D W et al. (2001) Immunization of mice with recombinant gp41 in a systemic prime/mucosal boost protocol induces HIV-1-specific serum IgG and secretory IgA antibodies. Vaccine 19:3990-4001
Vajdy, M; Veazey, R; Tham, I et al. (2001) Early immunologic events in mucosal and systemic lymphoid tissues after intrarectal inoculation with simian immunodeficiency virus. J Infect Dis 184:1007-14
Vajdy, M; Veazey, R S; Knight, H K et al. (2000) Differential effects of simian immunodeficiency virus infection on immune inductive and effector sites in the rectal mucosa of rhesus macaques. Am J Pathol 157:485-95
Wang, S W; Kozlowski, P A; Schmelz, G et al. (2000) Effective induction of simian immunodeficiency virus-specific systemic and mucosal immune responses in primates by vaccination with proviral DNA producing intact but noninfectious virions. J Virol 74:10514-22

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