Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI035466-03
Application #
2071142
Study Section
AIDS and Related Research Study Section 2 (ARRB)
Project Start
1994-09-01
Project End
1998-05-31
Budget Start
1996-06-01
Budget End
1997-05-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
St. Luke's-Roosevelt Institute for Health Sciences
Department
Type
DUNS #
City
New York
State
NY
Country
United States
Zip Code
10019
Sova, P; Chao, W; Volsky, D J (1997) The redox state of cysteines in human immunodeficiency virus type 1 Vif in infected cells and in virions. Biochem Biophys Res Commun 240:257-60
Kotler, M; Simm, M; Zhao, Y S et al. (1997) Human immunodeficiency virus type 1 (HIV-1) protein Vif inhibits the activity of HIV-1 protease in bacteria and in vitro. J Virol 71:5774-81
Simm, M; Pekarskaya, O; Volsky, D J (1996) Synthesis of full-length viral DNA in CD4-positive membrane vesicles exposed to HIV-1. A model for studies of early stages of the hiv-1 life cycle. J Biol Chem 271:28266-70
Chowdhury, I H; Chao, W; Potash, M J et al. (1996) vif-negative human immunodeficiency virus type 1 persistently replicates in primary macrophages, producing attenuated progeny virus. J Virol 70:5336-45
Simm, M; Chao, W; Pekarskaya, O et al. (1996) Genetic variability and function of the long terminal repeat from syncytium-inducing and non-syncytium-inducing human immunodeficiency virus type 1. AIDS Res Hum Retroviruses 12:801-9
Simm, M; Shahabuddin, M; Chao, W et al. (1995) Aberrant Gag protein composition of a human immunodeficiency virus type 1 vif mutant produced in primary lymphocytes. J Virol 69:4582-6
Sova, P; van Ranst, M; Gupta, P et al. (1995) Conservation of an intact human immunodeficiency virus type 1 vif gene in vitro and in vivo. J Virol 69:2557-64
Volsky, D J; Potash, M J; Simm, M et al. (1995) The human immunodeficiency virus type 1 vif gene: the road from an accessory to an essential role in human immunodeficiency virus type 1 replication. Curr Top Microbiol Immunol 193:157-68