Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
7R01AI035667-04
Application #
2607827
Study Section
Experimental Virology Study Section (EVR)
Project Start
1994-12-01
Project End
1999-11-30
Budget Start
1997-09-01
Budget End
1997-11-30
Support Year
4
Fiscal Year
1997
Total Cost
Indirect Cost
Name
Children's Hospital of Philadelphia
Department
Type
DUNS #
073757627
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Milstone, Aaron M; Petrella, JenniElizabeth; Sanchez, Melissa D et al. (2005) Interaction with coxsackievirus and adenovirus receptor, but not with decay-accelerating factor (DAF), induces A-particle formation in a DAF-binding coxsackievirus B3 isolate. J Virol 79:655-60
Chen, Zhi; Ahonen, Matti; Hamalainen, Heli et al. (2002) High-efficiency gene transfer to primary T lymphocytes by recombinant adenovirus vectors. J Immunol Methods 260:79-89
Fechner, H; Wang, X; Wang, H et al. (2000) Trans-complementation of vector replication versus Coxsackie-adenovirus-receptor overexpression to improve transgene expression in poorly permissive cancer cells. Gene Ther 7:1954-68
Okegawa, T; Li, Y; Pong, R C et al. (2000) The dual impact of coxsackie and adenovirus receptor expression on human prostate cancer gene therapy. Cancer Res 60:5031-6
van Raaij, M J; Chouin, E; van der Zandt, H et al. (2000) Dimeric structure of the coxsackievirus and adenovirus receptor D1 domain at 1.7 A resolution. Structure 8:1147-55
Pickles, R J; Fahrner, J A; Petrella, J M et al. (2000) Retargeting the coxsackievirus and adenovirus receptor to the apical surface of polarized epithelial cells reveals the glycocalyx as a barrier to adenovirus-mediated gene transfer. J Virol 74:6050-7
Dickeson, S K; Mathis, N L; Rahman, M et al. (1999) Determinants of ligand binding specificity of the alpha(1)beta(1) and alpha(2)beta(1) integrins. J Biol Chem 274:32182-91
Wang, X; Bergelson, J M (1999) Coxsackievirus and adenovirus receptor cytoplasmic and transmembrane domains are not essential for coxsackievirus and adenovirus infection. J Virol 73:2559-62
Li, Y; Pong, R C; Bergelson, J M et al. (1999) Loss of adenoviral receptor expression in human bladder cancer cells: a potential impact on the efficacy of gene therapy. Cancer Res 59:325-30
Bergelson, J M (1999) Receptors mediating adenovirus attachment and internalization. Biochem Pharmacol 57:975-9

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