Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI035960-03
Application #
2071963
Study Section
Special Emphasis Panel (SRC (25))
Project Start
1994-05-01
Project End
1999-01-31
Budget Start
1996-02-01
Budget End
1997-01-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Ohio State University
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
098987217
City
Columbus
State
OH
Country
United States
Zip Code
43210

  Publications

Song, Fei; Wardrop, Richard M; Gienapp, Ingrid E et al. (2008) The Peyer's patch is a critical immunoregulatory site for mucosal tolerance in experimental autoimmune encephalomylelitis (EAE). J Autoimmun 30:230-7
Whitacre, Caroline C; Song, Fei; Wardrop 3rd, Richard M et al. (2004) Regulation of autoreactive T cell function by oral tolerance to self-antigens. Ann N Y Acad Sci 1029:172-9
Song, Fei; Gienapp, Ingrid E; Wang, Xianming et al. (2002) Activation of Vbeta8 T cells affects spontaneous EAE in MBP TCR transgenic mice. J Neuroimmunol 123:112-22
Song, Fei; Wardrop, Richard M; Gienapp, Ingrid E et al. (2002) Differences between two strains of myelin basic protein (MBP) TCR transgenic mice: implications for tolerance induction. J Autoimmun 18:27-37
Meyer, A L; Benson, J; Song, F et al. (2001) Rapid depletion of peripheral antigen-specific T cells in TCR-transgenic mice after oral administration of myelin basic protein. J Immunol 166:5773-81
Benson, J M; Campbell, K A; Guan, Z et al. (2000) T-cell activation and receptor downmodulation precede deletion induced by mucosally administered antigen. J Clin Invest 106:1031-8
Dowdell, K C; Gienapp, I E; Stuckman, S et al. (1999) Neuroendocrine modulation of chronic relapsing experimental autoimmune encephalomyelitis: a critical role for the hypothalamic-pituitary-adrenal axis. J Neuroimmunol 100:243-51
Benson, J M; Stuckman, S S; Cox, K L et al. (1999) Oral administration of myelin basic protein is superior to myelin in suppressing established relapsing experimental autoimmune encephalomyelitis. J Immunol 162:6247-54
Goldman-Brezinski, S; Brezinski, K; Zhang, X M et al. (1998) Effects of oral tolerance induction by myelin basic protein on Vbeta8+ Lewis rat T cells. J Neurosci Res 51:67-75
Jewell, S D; Gienapp, I E; Cox, K L et al. (1998) Oral tolerance as therapy for experimental autoimmune encephalomyelitis and multiple sclerosis: demonstration of T cell anergy. Immunol Cell Biol 76:74-82

Showing the most recent 10 out of 18 publications