Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI036900-02
Application #
2073424
Study Section
Allergy and Immunology Study Section (ALY)
Project Start
1995-09-01
Project End
2000-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of MD Biotechnology Institute
Department
Type
Organized Research Units
DUNS #
City
Baltimore
State
MD
Country
United States
Zip Code
21202
Yang, Xinbo; Chen, Guobing; Weng, Nan-Ping et al. (2017) Structural basis for clonal diversity of the human T-cell response to a dominant influenza virus epitope. J Biol Chem 292:18618-18627
Chen, Guobing; Yang, Xinbo; Ko, Annette et al. (2017) Sequence and Structural Analyses Reveal Distinct and Highly Diverse Human CD8+ TCR Repertoires to Immunodominant Viral Antigens. Cell Rep 19:569-583
Li, Yili; Pierce, Brian G; Wang, Qian et al. (2015) Structural basis for penetration of the glycan shield of hepatitis C virus E2 glycoprotein by a broadly neutralizing human antibody. J Biol Chem 290:10117-25
He, Yanan; Rangarajan, Sneha; Kerzic, Melissa et al. (2015) Identification of the Docking Site for CD3 on the T Cell Receptor ? Chain by Solution NMR. J Biol Chem 290:19796-805
Yang, Xinbo; Gao, Mingming; Chen, Guobing et al. (2015) Structural Basis for Clonal Diversity of the Public T Cell Response to a Dominant Human Cytomegalovirus Epitope. J Biol Chem 290:29106-19
Rangarajan, Sneha; Mariuzza, Roy A (2014) T cell receptor bias for MHC: co-evolution or co-receptors? Cell Mol Life Sci 71:3059-68
Holland, Stephen J; Gao, Mingming; Hirano, Masayuki et al. (2014) Selection of the lamprey VLRC antigen receptor repertoire. Proc Natl Acad Sci U S A 111:14834-9
Li, Yili; Yin, Yiyuan; Mariuzza, Roy A (2013) Structural and biophysical insights into the role of CD4 and CD8 in T cell activation. Front Immunol 4:206
Chen, Shuming; Li, Yili; Depontieu, Florence R et al. (2013) Structure-based design of altered MHC class II-restricted peptide ligands with heterogeneous immunogenicity. J Immunol 191:5097-106
Deng, Lu; Luo, Ming; Velikovsky, Alejandro et al. (2013) Structural insights into the evolution of the adaptive immune system. Annu Rev Biophys 42:191-215

Showing the most recent 10 out of 44 publications