Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI037115-03
Application #
2073734
Study Section
Special Emphasis Panel (SRC (84))
Project Start
1994-09-30
Project End
1999-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Mount Sinai School of Medicine
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
City
New York
State
NY
Country
United States
Zip Code
10029
Radu, D L; Antohi, S; Bot, A et al. (2001) Effect of maternal antibodies on influenza virus-specific immune response elicited by inactivated virus and naked DNA. Scand J Immunol 53:475-82
Bot, A; Bot, S; Garcia-Sastre, A et al. (1998) Protective cellular immunity against influenza virus induced by plasmid inoculation of newborn mice. Dev Immunol 5:197-210
Antohi, S; Bot, A; Manfield, L et al. (1998) The reactivity pattern of hemagglutinin-specific clonotypes from mice immunized as neonates or adults with naked DNA. Int Immunol 10:663-8
Bot, A; Bot, S; Bona, C (1998) Enhanced protection against influenza virus of mice immunized as newborns with a mixture of plasmids expressing hemagglutinin and nucleoprotein. Vaccine 16:1675-82
Bot, A; Casares, S; Bot, S et al. (1998) Cellular mechanisms involved in protection against influenza virus infection in transgenic mice expressing a TCR receptor specific for class II hemagglutinin peptide in CD4+ and CD8+ T cells. J Immunol 160:4500-7
Bot, A; Antohi, S; Bot, S et al. (1997) Induction of humoral and cellular immunity against influenza virus by immunization of newborn mice with a plasmid bearing a hemagglutinin gene. Int Immunol 9:1641-50
Casares, S; Inaba, K; Brumeanu, T D et al. (1997) Antigen presentation by dendritic cells after immunization with DNA encoding a major histocompatibility complex class II-restricted viral epitope. J Exp Med 186:1481-6
Bot, A; Antohi, S; Bona, C (1997) Immune response of neonates elicited by somatic transgene vaccination with naked DNA. Front Biosci 2:d173-88
Bot, A; Bot, S; Antohi, S et al. (1996) Kinetics of generation and persistence on membrane class II molecules of a viral peptide expressed on foreign and self proteins. J Immunol 157:3436-42
Bot, A; Nangpal, A; Pricop, L et al. (1996) V lambda-light chain genes reconstitute immune responses to defined carbohydrate antigens or haptens by utilizing different VH genes. Mol Immunol 33:1359-68

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