Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI037692-02
Application #
2074540
Study Section
Special Emphasis Panel (SRC (23))
Project Start
1995-03-15
Project End
2000-02-29
Budget Start
1996-03-01
Budget End
1997-02-28
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Massachusetts General Hospital
Department
Type
DUNS #
City
Boston
State
MA
Country
United States
Zip Code
02199
Thaiss, Cornelius C; Oura, Tetsu; Sasaki, Hajime et al. (2018) Importance of Hematopoietic Mixed Chimerism for Induction of Renal Allograft Tolerance in Nonhuman Primates. Transplantation :
Oura, Tetsu; Ko, Dicken S C; Boskovic, Svjetlan et al. (2016) Kidney Versus Islet Allograft Survival After Induction of Mixed Chimerism With Combined Donor Bone Marrow Transplantation. Cell Transplant 25:1331-41
Kawai, Tatsuo; Sachs, David H; Sykes, Megan et al. (2013) HLA-mismatched renal transplantation without maintenance immunosuppression. N Engl J Med 368:1850-2
Aoyama, A; Klarin, D; Yamada, Y et al. (2012) Low-dose IL-2 for In vivo expansion of CD4+ and CD8+ regulatory T cells in nonhuman primates. Am J Transplant 12:2532-7
Yamada, Y; Boskovic, S; Aoyama, A et al. (2012) Overcoming memory T-cell responses for induction of delayed tolerance in nonhuman primates. Am J Transplant 12:330-40
Yamada, Yohei; Aoyama, Akihiro; Tocco, Georges et al. (2012) Differential effects of denileukin diftitox IL-2 immunotoxin on NK and regulatory T cells in nonhuman primates. J Immunol 188:6063-70
Nadazdin, Ognjenka; Abrahamian, Gregory; Boskovic, Svjetlan et al. (2011) Stem cell mobilization and collection for induction of mixed chimerism and renal allograft tolerance in cynomolgus monkeys. J Surg Res 168:294-300
Murakami, Toru; Cosimi, A Benedict; Kawai, Tatsuo (2009) Mixed chimerism to induce tolerance: lessons learned from nonhuman primates. Transplant Rev (Orlando) 23:19-24
Traum, Avram Z; Kawai, Tatsuo; Vacanti, Joseph P et al. (2008) The need for tolerance in pediatric organ transplantation. Pediatrics 121:1258-60
Kawai, Tatsuo; Cosimi, A Benedict; Spitzer, Thomas R et al. (2008) HLA-mismatched renal transplantation without maintenance immunosuppression. N Engl J Med 358:353-61

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