Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
1R01AI038245-01A3
Application #
2075226
Study Section
AIDS and Related Research Study Section 1 (ARRA)
Project Start
1996-07-01
Project End
1999-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Picower Institute for Medical Research
Department
Type
DUNS #
City
Manhasset
State
NY
Country
United States
Zip Code
11030
Yurchenko, Vyacheslav; Pushkarsky, Tatiana; Li, Jian-Hua et al. (2005) Regulation of CD147 cell surface expression: involvement of the proline residue in the CD147 transmembrane domain. J Biol Chem 280:17013-9
Yurchenko, Vyacheslav; Zybarth, Gabriele; O'Connor, Matthew et al. (2002) Active site residues of cyclophilin A are crucial for its signaling activity via CD147. J Biol Chem 277:22959-65
Alfano, M; Vallanti, G; Biswas, P et al. (2001) The binding subunit of pertussis toxin inhibits HIV replication in human macrophages and virus expression in chronically infected promonocytic U1 cells. J Immunol 166:1863-70
Pushkarsky, T; Zybarth, G; Dubrovsky, L et al. (2001) CD147 facilitates HIV-1 infection by interacting with virus-associated cyclophilin A. Proc Natl Acad Sci U S A 98:6360-5
Alfano, M; Pushkarsky, T; Poli, G et al. (2000) The B-oligomer of pertussis toxin inhibits human immunodeficiency virus type 1 replication at multiple stages. J Virol 74:8767-70
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Alfano, M; Schmidtmayerova, H; Bukrinsky, M (1998) Bacterial lipopolysaccharide is a potent inhibitor of HIV-1 replication in T lymphocytes and macrophages. AIDS 12:1724-6
Raabe, T; Bukrinsky, M; Currie, R A (1998) Relative contribution of transcription and translation to the induction of tumor necrosis factor-alpha by lipopolysaccharide. J Biol Chem 273:974-80
Schmidtmayerova, H; Alfano, M; Nuovo, G et al. (1998) Human immunodeficiency virus type 1 T-lymphotropic strains enter macrophages via a CD4- and CXCR4-mediated pathway: replication is restricted at a postentry level. J Virol 72:4633-42

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