Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
1R01AI038667-01A1
Application #
2075747
Study Section
AIDS and Related Research Study Section 4 (ARRD)
Project Start
1996-07-01
Project End
1999-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Southern Research Institute
Department
Type
DUNS #
006900526
City
Birmingham
State
AL
Country
United States
Zip Code
35205
Reynolds, Robert C; Campbell, Shiela R; Fairchild, Ralph G et al. (2007) Novel boron-containing, nonclassical antifolates: synthesis and preliminary biological and structural evaluation. J Med Chem 50:3283-9
Pathak, A K; Pathak, V; Khare, N K et al. (2001) Synthesis of disaccharides related to the mycobacterial arabinogalactan. Carbohydr Lett 4:117-22
Suling, W J; Maddry, J A (2001) Antimycobacterial activity of 1-deaza-7,8-dihydropteridine derivatives against Mycobacterium tuberculosis and Mycobacterium avium complex in vitro. J Antimicrob Chemother 47:451-4
Pathak, A K; Pathak, V; Maddry, J A et al. (2001) Studies on alpha(1-->5) linked octyl arabinofuranosyl disaccharides for mycobacterial arabinosyl transferase activity. Bioorg Med Chem 9:3145-51
Pathak, A K; Besra, G S; Crick, D et al. (1999) Studies on beta-D-Gal(f)-(1-->4)-alpha-L-Rha(p) octyl analogues as substrates for mycobacterial galactosyl transferase activity. Bioorg Med Chem 7:2407-13
Reynolds, R C; Bansal, N; Rose, J et al. (1999) Ethambutol-sugar hybrids as potential inhibitors of mycobacterial cell-wall biosynthesis. Carbohydr Res 317:164-79
Maddry, J A; Bansal, N; Bermudez, L E et al. (1998) Homologated aza analogs of arabinose as antimycobacterial agents. Bioorg Med Chem Lett 8:237-42