Tolerance Induction by Monoclonal Antibodies

Lipsky, Peter E.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Allergy and Infectious Diseases (NIAID)
• Type: Research Project (R01)
• Project #: 1R01AI039230-01
• Application #: 2076328
• Study Section: Special Emphasis Panel (SRC (40))
• Project Start: 1996-05-01
• Project End: 2001-04-30
• Budget Start: 1996-05-01
• Budget End: 1997-04-30
• Support Year: 1
• Fiscal Year: 1996

Institution

• Name: University of Texas Sw Medical Center Dallas
• Department: Internal Medicine/Medicine
• Type: Schools of Medicine
• City: Dallas
• State: TX
• Country: United States
• Zip Code: 75390

Publications

Tao, Xuelian; Fan, Fred; Hoffmann, Victoria et al. (2008) Effective therapy for nephritis in (NZB x NZW)F1 mice with triptolide and tripdiolide, the principal active components of the Chinese herbal remedy Tripterygium wilfordii Hook F. Arthritis Rheum 58:1774-83

Cravens, P D; Hayashida, K; Davis, L S et al. (2007) Human peripheral blood dendritic cells and monocyte subsets display similar chemokine receptor expression profiles with differential migratory responses. Scand J Immunol 65:514-24

Schulze-Koops, H; Davis, L S; Haverty, T P et al. (1998) Reduction of Th1 cell activity in the peripheral circulation of patients with rheumatoid arthritis after treatment with a non-depleting humanized monoclonal antibody to CD4. J Rheumatol 25:2065-76

Schulze-Koops, H; Lipsky, P E; Davis, L S (1998) Human memory T cell differentiation into Th2-like effector cells is dependent on IL-4 and CD28 stimulation and inhibited by TCR ligation. Eur J Immunol 28:2517-29

Schulze-Koops, H; Davis, L S; Kavanaugh, A F et al. (1997) Elevated cytokine messenger RNA levels in the peripheral blood of patients with rheumatoid arthritis suggest different degrees of myeloid cell activation. Arthritis Rheum 40:639-47