Role of the SIV/HIV Transmembrane Subunit of Env in AIDS

Gardner, Murray Briggs

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Allergy and Infectious Diseases (NIAID)
• Type: Research Project (R01)
• Project #: 1R01AI039415-01
• Application #: 2076489
• Study Section: AIDS and Related Research Study Section 3 (ARRC)
• Project Start: 1996-02-01
• Project End: 2000-01-31
• Budget Start: 1996-02-01
• Budget End: 1997-01-31
• Support Year: 1
• Fiscal Year: 1996

Institution

• Name: University of California Davis
• Department: Pathology
• Type: Schools of Medicine
• DUNS #: 094878337
• City: Davis
• State: CA
• Country: United States
• Zip Code: 95618

Publications

Kalia, Vandana; Sarkar, Surojit; Gupta, Phalguni et al. (2005) Antibody neutralization escape mediated by point mutations in the intracytoplasmic tail of human immunodeficiency virus type 1 gp41. J Virol 79:2097-107

Shacklett, Barbara L; Shaw, Karen E S; Adamson, Lou A et al. (2002) Live, attenuated simian immunodeficiency virus SIVmac-M4, with point mutations in the Env transmembrane protein intracytoplasmic domain, provides partial protection from mucosal challenge with pathogenic SIVmac251. J Virol 76:11365-78

Luciw, P A; Shaw, K E; Shacklett, B L et al. (1998) Importance of the intracytoplasmic domain of the simian immunodeficiency virus (SIV) envelope glycoprotein for pathogenesis. Virology 252:9-16