Abstract

This competing renewal application investigates the persistence, ecology and surveillance of mosquito-borne encephalitis viruses in seasonal wetland and agricultural habitats in California. Proposed research tests the hypothesis that resident and/or transient birds associated with seasonal wetlands are responsible for the interseasonal maintenance and vernal amplification of western equine encephalomyelitis (WEE) and St. Louis encephalitis (SLE) viruses and serves as a source of virus for adjacent and distant receptive habitats. Virus ecology at wetlands in the Coachella Valley of southeastern California with consistent enzootic activity will be compared with wetlands in the southern San Joaquin Valley where virus activity currently is intermittent.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI039483-03
Application #
6373514
Study Section
Special Emphasis Panel (ZRG1-TMP (01))
Program Officer
Meegan, James M
Project Start
1999-09-28
Project End
2003-08-31
Budget Start
2001-09-01
Budget End
2002-08-31
Support Year
3
Fiscal Year
2001
Total Cost
$338,844
Indirect Cost

  Institution

Name
University of California Davis
Department
Public Health & Prev Medicine
Type
Schools of Veterinary Medicine
DUNS #
094878337
City
Davis
State
CA
Country
United States
Zip Code
95618

  Publications

Oviedo, Marco V Neira; Romoser, William S; James, Calvin Bl et al. (2011) Infection dynamics of western equine encephalomyelitis virus (Togaviridae: Alphavirus) in four strains of Culex tarsalis (Diptera: Culicidae): an immunocytochemical study. Res Rep Trop Med 2011:65-77
Reisen, William K; Wheeler, Sarah S; Garcia, Sandra et al. (2010) Migratory birds and the dispersal of arboviruses in California. Am J Trop Med Hyg 83:808-15
Reisen, William K; Martinez, Vincent M; Fang, Ying et al. (2006) Role of California (Callipepla californica) and Gambel's (Callipepla gambelii) quail in the ecology of mosquito-borne encephalitis viruses in California, USA. Vector Borne Zoonotic Dis 6:248-60
Mahmood, Farida; Chiles, Robert E; Fang, Ying et al. (2006) Effects of time after infection, mosquito genotype, and infectious viral dose on the dynamics of Culex tarsalis vector competence for western equine encephalomyelitis virus. J Am Mosq Control Assoc 22:272-81
Reisen, W K; Fang, Y; Martinez, V M (2005) Avian host and mosquito (Diptera: Culicidae) vector competence determine the efficiency of West Nile and St. Louis encephalitis virus transmission. J Med Entomol 42:367-75
Reisen, William K; Chiles, Robert E; Martinez, Vincent M et al. (2004) Encephalitis virus persistence in California birds: experimental infections in mourning doves (Zenaidura macroura). J Med Entomol 41:462-6
Mahmood, Farida; Chiles, Robert E; Fang, Ying et al. (2004) Role of nestling mourning doves and house finches as amplifying hosts of St. Louis encephalitis virus. J Med Entomol 41:965-72
Reisen, William K; Chiles, Robert; Martinez, Vincent et al. (2004) Effect of dose on house finch infection with western equine encephalomyelitis and St. Louis encephalitis viruses. J Med Entomol 41:978-81
Chiles, Robert E; Green, Emily N; Fang, Ying et al. (2004) Blinded laboratory comparison of the in situ enzyme immunoassay, the VecTest wicking assay, and a reverse transcription-polymerase chain reaction assay to detect mosquitoes infected with West Nile and St. Louis encephalitis viruses. J Med Entomol 41:539-44
Reisen, William K; Chiles, Robert E; Green, Emily N et al. (2003) Effects of immunosuppression on encephalitis virus infection in the house finch, Carpodacus mexicanus. J Med Entomol 40:206-14

Showing the most recent 10 out of 15 publications