Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI042949-05
Application #
6688438
Study Section
Allergy and Immunology Study Section (ALY)
Program Officer
Esch, Thomas R
Project Start
1998-07-01
Project End
2007-11-30
Budget Start
2003-12-01
Budget End
2004-11-30
Support Year
5
Fiscal Year
2004
Total Cost
$312,000
Indirect Cost

  Institution

Name
University of Texas Sw Medical Center Dallas
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
800771545
City
Dallas
State
TX
Country
United States
Zip Code
75390

  Publications

Pastor, Silvia; Minguela, Alfredo; Mi, Wentao et al. (2009) Autoantigen immunization at different sites reveals a role for anti-inflammatory effects of IFN-gamma in regulating susceptibility to experimental autoimmune encephalomyelitis. J Immunol 182:5268-75
Mi, Wentao; Wanjie, Sylvia; Lo, Su-Tang et al. (2008) Targeting the neonatal fc receptor for antigen delivery using engineered fc fragments. J Immunol 181:7550-61
Minguela, Alfredo; Pastor, Silvia; Mi, Wentao et al. (2007) Feedback regulation of murine autoimmunity via dominant anti-inflammatory effects of interferon gamma. J Immunol 178:134-44
Pastor, Silvia; Vaccaro, Carlos G; Minguela, Alfredo et al. (2006) Analyses of TCR clustering at the T cell-antigen-presenting cell interface and its impact on the activation of naive CD4+ T cells. Int Immunol 18:1615-25
Huang, Jason C; Ober, Raimund J; Ward, E Sally (2005) The central residues of a T cell receptor sequence motif are key determinants of autoantigen recognition in murine experimental autoimmune encephalomyelitis. Eur J Immunol 35:299-304
Huang, Jason C; Vestberg, Mikael; Minguela, Alfredo et al. (2004) Analysis of autoreactive T cells associated with murine collagen-induced arthritis using peptide-MHC multimers. Int Immunol 16:283-93
Huang, Jason C; Han, Mei; Minguela, Alfredo et al. (2003) T cell recognition of distinct peptide:I-Au conformers in murine experimental autoimmune encephalomyelitis. J Immunol 171:2467-77
He, Xiao-lin; Radu, Caius; Sidney, John et al. (2002) Structural snapshot of aberrant antigen presentation linked to autoimmunity: the immunodominant epitope of MBP complexed with I-Au. Immunity 17:83-94
Deng, Caishu; Minguela, Alfredo; Hussain, Rehana Z et al. (2002) Expression of the tyrosine phosphatase SRC homology 2 domain-containing protein tyrosine phosphatase 1 determines T cell activation threshold and severity of experimental autoimmune encephalomyelitis. J Immunol 168:4511-8
Garcia, K C; Radu, C G; Ho, J et al. (2001) Kinetics and thermodynamics of T cell receptor- autoantigen interactions in murine experimental autoimmune encephalomyelitis. Proc Natl Acad Sci U S A 98:6818-23

Showing the most recent 10 out of 18 publications