Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI043534-05
Application #
6746868
Study Section
Immunobiology Study Section (IMB)
Program Officer
Kirkham, Perry M
Project Start
2000-06-01
Project End
2005-06-30
Budget Start
2004-06-01
Budget End
2005-06-30
Support Year
5
Fiscal Year
2004
Total Cost
$273,000
Indirect Cost
Name
University of Massachusetts Medical School Worcester
Department
Genetics
Type
Schools of Medicine
DUNS #
603847393
City
Worcester
State
MA
Country
United States
Zip Code
01655
Selimyan, Roza; Gerstein, Rachel M; Ivanova, Irina et al. (2013) Localized DNA demethylation at recombination intermediates during immunoglobulin heavy chain gene assembly. PLoS Biol 11:e1001475
Guikema, Jeroen E J; Gerstein, Rachel M; Linehan, Erin K et al. (2011) Apurinic/apyrimidinic endonuclease 2 is necessary for normal B cell development and recovery of lymphoid progenitors after chemotherapeutic challenge. J Immunol 186:1943-50
Priyadharshini, Bhavana; Welsh, Raymond M; Greiner, Dale L et al. (2010) Maturation-dependent licensing of naive T cells for rapid TNF production. PLoS One 5:e15038
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Gerstein, Rachel M (2009) Deciding the decider: Mef2c in hematopoiesis. Nat Immunol 10:235-6
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Pilbeam, Kristy; Basse, Per; Brossay, Laurent et al. (2008) The ontogeny and fate of NK cells marked by permanent DNA rearrangements. J Immunol 180:1432-41
Kuo, Ya-Huei; Gerstein, Rachel M; Castilla, Lucio H (2008) Cbfbeta-SMMHC impairs differentiation of common lymphoid progenitors and reveals an essential role for RUNX in early B-cell development. Blood 111:1543-51
Hoek, Kristen L; Antony, Pierre; Lowe, John et al. (2006) Transitional B cell fate is associated with developmental stage-specific regulation of diacylglycerol and calcium signaling upon B cell receptor engagement. J Immunol 177:5405-13
Borghesi, Lisa; Hsu, Lih-Yun; Miller, Juli P et al. (2004) B lineage-specific regulation of V(D)J recombinase activity is established in common lymphoid progenitors. J Exp Med 199:491-502

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