Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI043933-02
Application #
6170951
Study Section
Virology Study Section (VR)
Program Officer
Meegan, James M
Project Start
1999-07-15
Project End
2003-06-30
Budget Start
2000-07-01
Budget End
2001-06-30
Support Year
2
Fiscal Year
2000
Total Cost
$248,068
Indirect Cost
Name
State University of New York at Buffalo
Department
Biochemistry
Type
Schools of Medicine
DUNS #
038633251
City
Buffalo
State
NY
Country
United States
Zip Code
14260
Christen, Linda A; Piacente, Sarah; Mohamed, Mohamed R et al. (2008) Vaccinia virus early gene transcription termination factors VTF and Rap94 interact with the U9 termination motif in the nascent RNA in a transcription ternary complex. Virology 376:225-35
Piacente, Sarah; Christen, Linda; Dickerman, Benjamin et al. (2008) Determinants of vaccinia virus early gene transcription termination. Virology 376:211-24
Mohamed, Mohamed Ragaa; Piacente, Sarah C; Dickerman, Benjamin et al. (2006) Effect of UTP sugar and base modifications on vaccinia virus early gene transcription. Virology 349:359-70
Mohamed, Mohamed Ragaa; Niles, Edward G (2004) UUUUUNU oligonucleotide inhibition of RNA synthesis in vaccinia virus cores. Virology 324:493-500
Shalaby, Kamal A; Yin, Lei; Thakur, Arvind et al. (2003) Protection against Schistosoma mansoni utilizing DNA vaccination with genes encoding Cu/Zn cytosolic superoxide dismutase, signal peptide-containing superoxide dismutase and glutathione peroxidase enzymes. Vaccine 22:130-6
Mohamed, Mohamed Ragaa; Niles, Edward G (2003) UUUUUNU stimulation of vaccinia virus early gene transcription termination. Oligonucleotide sequence and structural requirements for stimulation of premature termination in vitro. J Biol Chem 278:39534-41
Mohamed, Mohamed Ragaa; Niles, Edward G (2003) UUUUUNU oligonucleotide stimulation of vaccinia virus early gene transcription termination, in trans. J Biol Chem 278:11794-801
Piacente, Sarah C; Christen, Linda A; Mohamed, Mohamed Ragaa et al. (2003) Effect of selected mutations in the C-terminal region of the vaccinia virus nucleoside triphosphate phosphohydrolase I on binding to the H4L subunit of the viral RNA polymerase and early gene transcription termination in vitro. Virology 310:109-17
Mohamed, Mohamed R; Christen, Linda A; Niles, Edward G (2002) Antibodies directed against an epitope in the N-terminal region of the H4L subunit of the vaccinia virus RNA polymerase inhibit both transcription initiation and transcription termination, in vitro. Virology 299:142-53
Mohamed, M R; Niles, E G (2001) The viral RNA polymerase H4L subunit is required for Vaccinia virus early gene transcription termination. J Biol Chem 276:20758-65

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