Antigen Presentation by CD1

Porcelli, Steven A.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Allergy and Infectious Diseases (NIAID)
• Type: Research Project (R01)
• Project #: 1R01AI048933-01
• Application #: 6291214
• Study Section: Special Emphasis Panel (ZAI1-MSQ-I (S3))
• Program Officer: Ash-Shaheed, Belinda
• Project Start: 2000-08-01
• Project End: 2005-07-31
• Budget Start: 2000-08-01
• Budget End: 2001-07-31
• Support Year: 1
• Fiscal Year: 2000
• Total Cost: $263,114

Institution

• Name: Albert Einstein College of Medicine
• Department: Microbiology/Immun/Virology
• Type: Schools of Medicine
• DUNS #: 009095365
• City: Bronx
• State: NY
• Country: United States
• Zip Code: 10461

Publications

Van Rhijn, Ildiko; Koets, Ad P; Im, Jin Seon et al. (2006) The bovine CD1 family contains group 1 CD1 proteins, but no functional CD1d. J Immunol 176:4888-93

Russano, Anna M; Agea, Elisabetta; Corazzi, Lanfranco et al. (2006) Recognition of pollen-derived phosphatidyl-ethanolamine by human CD1d-restricted gamma delta T cells. J Allergy Clin Immunol 117:1178-84

Agea, Elisabetta; Russano, Anna; Bistoni, Onelia et al. (2005) Human CD1-restricted T cell recognition of lipids from pollens. J Exp Med 202:295-308

Sieling, Peter A; Torrelles, Jordi B; Stenger, Steffen et al. (2005) The human CD1-restricted T cell repertoire is limited to cross-reactive antigens: implications for host responses against immunologically related pathogens. J Immunol 174:2637-44

Yu, Karl O A; Im, Jin S; Molano, Alberto et al. (2005) Modulation of CD1d-restricted NKT cell responses by using N-acyl variants of alpha-galactosylceramides. Proc Natl Acad Sci U S A 102:3383-8

Rao, Vivek; Fujiwara, Nagatoshi; Porcelli, Steven A et al. (2005) Mycobacterium tuberculosis controls host innate immune activation through cyclopropane modification of a glycolipid effector molecule. J Exp Med 201:535-43

Dao, D N; Kremer, L; Guerardel, Y et al. (2004) Mycobacterium tuberculosis lipomannan induces apoptosis and interleukin-12 production in macrophages. Infect Immun 72:2067-74

Sidobre, Stephane; Hammond, Kirsten J L; Benazet-Sidobre, Lise et al. (2004) The T cell antigen receptor expressed by Valpha14i NKT cells has a unique mode of glycosphingolipid antigen recognition. Proc Natl Acad Sci U S A 101:12254-9

Hunger, Robert E; Sieling, Peter A; Ochoa, Maria Teresa et al. (2004) Langerhans cells utilize CD1a and langerin to efficiently present nonpeptide antigens to T cells. J Clin Invest 113:701-8

Amprey, Joseph L; Im, Jin S; Turco, Salvatore J et al. (2004) A subset of liver NK T cells is activated during Leishmania donovani infection by CD1d-bound lipophosphoglycan. J Exp Med 200:895-904