Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI052164-02
Application #
6767632
Study Section
Immunological Sciences Study Section (IMS)
Program Officer
Plaut, Marshall
Project Start
2003-07-01
Project End
2005-12-31
Budget Start
2004-01-01
Budget End
2004-12-31
Support Year
2
Fiscal Year
2004
Total Cost
$308,000
Indirect Cost
Name
University of Colorado Denver
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
041096314
City
Aurora
State
CO
Country
United States
Zip Code
80045
Chen, Xueni; Negi, Surendra S; Liao, Sumei et al. (2016) Conformational IgE epitopes of peanut allergens Ara h 2 and Ara h 6. Clin Exp Allergy 46:1120-1128
Bernard, Hervé; Guillon, Blanche; Drumare, Marie-Françoise et al. (2015) Allergenicity of peanut component Ara h 2: Contribution of conformational versus linear hydroxyproline-containing epitopes. J Allergy Clin Immunol 135:1267-74.e1-8
Otsu, K; Guo, R; Dreskin, S C (2015) Epitope analysis of Ara h 2 and Ara h 6: characteristic patterns of IgE-binding fingerprints among individuals with similar clinical histories. Clin Exp Allergy 45:471-84
Koid, Audrey E; Chapman, Martin D; Hamilton, Robert G et al. (2014) Ara h 6 complements Ara h 2 as an important marker for IgE reactivity to peanut. J Agric Food Chem 62:206-13
Mills, K; Lay, J; Wu, W et al. (2014) Vitamin E, ?-tocopherol, diminishes ex vivo basophil response to dust mite allergen. Allergy 69:541-4
Chen, Xueni; Wang, Qian; El-Mezayen, Rabab et al. (2013) Ara h 2 and Ara h 6 have similar allergenic activity and are substantially redundant. Int Arch Allergy Immunol 160:251-8
Zhuang, Yonghua; Dreskin, Stephen C (2013) Redefining the major peanut allergens. Immunol Res 55:125-34
Kulis, M; Chen, X; Lew, J et al. (2012) The 2S albumin allergens of Arachis hypogaea, Ara h 2 and Ara h 6, are the major elicitors of anaphylaxis and can effectively desensitize peanut-allergic mice. Clin Exp Allergy 42:326-36
Zhuang, Yonghua; Durrani, Sandy; Hodges, Brittany D M et al. (2012) Expression of recombinant Ara h 6 in Pichia pastoris but not in Escherichia coli preserves allergic effector function and allows assessment of specific mutations. Mol Nutr Food Res 56:986-95
Martucci, Michael A; Dreskin, Stephen C (2011) Immunologic similarities between selected autoimmune diseases and peanut allergy: possible new therapeutic approaches. Curr Allergy Asthma Rep 11:334-9

Showing the most recent 10 out of 13 publications