Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI053148-02
Application #
6760043
Study Section
Tropical Medicine and Parasitology Study Section (TMP)
Program Officer
Rogers, Martin J
Project Start
2003-07-01
Project End
2007-12-31
Budget Start
2004-01-01
Budget End
2004-12-31
Support Year
2
Fiscal Year
2004
Total Cost
$337,500
Indirect Cost
Name
Drexel University
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
002604817
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Vaidya, Akhil B (2018) Reflections on an inflection: From virology to parasitology guided by POLARIS. PLoS Pathog 14:e1006941
Ke, Hangjun; Lewis, Ian A; Morrisey, Joanne M et al. (2015) Genetic investigation of tricarboxylic acid metabolism during the Plasmodium falciparum life cycle. Cell Rep 11:164-74
Balabaskaran Nina, Praveen; Morrisey, Joanne M; Ganesan, Suresh M et al. (2011) ATP synthase complex of Plasmodium falciparum: dimeric assembly in mitochondrial membranes and resistance to genetic disruption. J Biol Chem 286:41312-22
Balabaskaran Nina, Praveen; Dudkina, Natalya V; Kane, Lesley A et al. (2010) Highly divergent mitochondrial ATP synthase complexes in Tetrahymena thermophila. PLoS Biol 8:e1000418
Vaidya, Akhil B; Mather, Michael W (2009) Mitochondrial evolution and functions in malaria parasites. Annu Rev Microbiol 63:249-67
Mather, Michael W; Vaidya, Akhil B (2008) Mitochondria in malaria and related parasites: ancient, diverse and streamlined. J Bioenerg Biomembr 40:425-33
Vaidya, Akhil B; Painter, Heather J; Morrisey, Joanne M et al. (2008) The validity of mitochondrial dehydrogenases as antimalarial drug targets. Trends Parasitol 24:8-9
Mather, Michael W; Henry, Karl W; Vaidya, Akhil B (2007) Mitochondrial drug targets in apicomplexan parasites. Curr Drug Targets 8:49-60
Vaidya, Akhil B (2004) Mitochondrial and plastid functions as antimalarial drug targets. Curr Drug Targets Infect Disord 4:11-23