Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI053479-02
Application #
6688452
Study Section
Lung Biology and Pathology Study Section (LBPA)
Program Officer
Plaut, Marshall
Project Start
2002-12-15
Project End
2007-11-30
Budget Start
2003-12-01
Budget End
2004-11-30
Support Year
2
Fiscal Year
2004
Total Cost
$372,500
Indirect Cost
Name
Cincinnati Children's Hospital Medical Center
Department
Type
DUNS #
071284913
City
Cincinnati
State
OH
Country
United States
Zip Code
45229
Simon, Dagmar; Wardlaw, Andrew; Rothenberg, Marc E (2010) Organ-specific eosinophilic disorders of the skin, lung, and gastrointestinal tract. J Allergy Clin Immunol 126:3-13; quiz 14-5
Niese, Kathryn A; Chiaramonte, Monica G; Ellies, Lesley G et al. (2010) The cationic amino acid transporter 2 is induced in inflammatory lung models and regulates lung fibrosis. Respir Res 11:87
Niese, Kathryn A; Collier, Ann R; Hajek, Amanda R et al. (2009) Bone marrow cell derived arginase I is the major source of allergen-induced lung arginase but is not required for airway hyperresponsiveness, remodeling and lung inflammatory responses in mice. BMC Immunol 10:33
Zimmermann, Nives; Rothenberg, Marc E (2006) The arginine-arginase balance in asthma and lung inflammation. Eur J Pharmacol 533:253-62
Hogan, Simon P; Seidu, Luqman; Blanchard, Carine et al. (2006) Resistin-like molecule beta regulates innate colonic function: barrier integrity and inflammation susceptibility. J Allergy Clin Immunol 118:257-68
Rothenberg, Marc E; Doepker, Matthew P; Lewkowich, Ian P et al. (2006) Cationic amino acid transporter 2 regulates inflammatory homeostasis in the lung. Proc Natl Acad Sci U S A 103:14895-900
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Zimmermann, Nives; Mishra, Anil; King, Nina E et al. (2004) Transcript signatures in experimental asthma: identification of STAT6-dependent and -independent pathways. J Immunol 172:1815-24
Zimmermann, Nives; King, Nina E; Laporte, Johanne et al. (2003) Dissection of experimental asthma with DNA microarray analysis identifies arginase in asthma pathogenesis. J Clin Invest 111:1863-74