Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI053629-02
Application #
6755059
Study Section
Experimental Virology Study Section (EVR)
Program Officer
Lacourciere, Karen A
Project Start
2003-06-15
Project End
2007-11-30
Budget Start
2003-12-01
Budget End
2004-11-30
Support Year
2
Fiscal Year
2004
Total Cost
$267,750
Indirect Cost

  Institution

Name
Washington University
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
068552207
City
Saint Louis
State
MO
Country
United States
Zip Code
63130

  Publications

Stewart, Shaun M; Pekosz, Andrew (2012) The influenza C virus CM2 protein can alter intracellular pH, and its transmembrane domain can substitute for that of the influenza A virus M2 protein and support infectious virus production. J Virol 86:1277-81
Stewart, Shaun M; Pekosz, Andrew (2011) Mutations in the membrane-proximal region of the influenza A virus M2 protein cytoplasmic tail have modest effects on virus replication. J Virol 85:12179-87
Grantham, Michael L; Stewart, Shaun M; Lalime, Erin N et al. (2010) Tyrosines in the influenza A virus M2 protein cytoplasmic tail are critical for production of infectious virus particles. J Virol 84:8765-76
Stewart, Shaun M; Wu, Wai-Hong; Lalime, Erin N et al. (2010) The cholesterol recognition/interaction amino acid consensus motif of the influenza A virus M2 protein is not required for virus replication but contributes to virulence. Virology 405:530-8
Pekosz, Andrew; Newby, Celeste; Bose, Pulkit S et al. (2009) Sialic acid recognition is a key determinant of influenza A virus tropism in murine trachea epithelial cell cultures. Virology 386:61-7
Li, Yunsheng; Larrimer, Audrey; Curtiss, Teresa et al. (2009) Influenza virus assays based on virus-inducible reporter cell lines. Influenza Other Respir Viruses 3:241-51
Grantham, Michael L; Wu, Wai-Hong; Lalime, Erin N et al. (2009) Palmitoylation of the influenza A virus M2 protein is not required for virus replication in vitro but contributes to virus virulence. J Virol 83:8655-61
Pekosz, Andrew; Glass, Gregory E (2008) Emerging viral diseases. Md Med 9:11, 13-6
Wu, Wai-Hong; Pekosz, Andrew (2008) Extending the cytoplasmic tail of the influenza a virus M2 protein leads to reduced virus replication in vivo but not in vitro. J Virol 82:1059-63
Newby, Celeste M; Sabin, Leah; Pekosz, Andrew (2007) The RNA binding domain of influenza A virus NS1 protein affects secretion of tumor necrosis factor alpha, interleukin-6, and interferon in primary murine tracheal epithelial cells. J Virol 81:9469-80

Showing the most recent 10 out of 14 publications