Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI055962-02
Application #
6758521
Study Section
Special Emphasis Panel (ZRG1-BM-1 (01))
Program Officer
Alexander, William A
Project Start
2003-06-15
Project End
2007-11-30
Budget Start
2003-12-01
Budget End
2004-11-30
Support Year
2
Fiscal Year
2004
Total Cost
$421,562
Indirect Cost

  Institution

Name
Harvard University
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
047006379
City
Boston
State
MA
Country
United States
Zip Code
02115

  Publications

Zhang, Xuqing; Starnbach, Michael N (2015) An Excess of the Proinflammatory Cytokines IFN-? and IL-12 Impairs the Development of the Memory CD8+ T Cell Response to Chlamydia trachomatis. J Immunol 195:1665-75
Nogueira, Catarina V; Zhang, Xuqing; Giovannone, Nicholas et al. (2015) Protective immunity against Chlamydia trachomatis can engage both CD4+ and CD8+ T cells and bridge the respiratory and genital mucosae. J Immunol 194:2319-29
Fankhauser, Sarah C; Starnbach, Michael N (2014) PD-L1 limits the mucosal CD8+ T cell response to Chlamydia trachomatis. J Immunol 192:1079-90
Jehl, Stephanie P; Nogueira, Catarina V; Zhang, Xuqing et al. (2012) IFN? inhibits the cytosolic replication of Shigella flexneri via the cytoplasmic RNA sensor RIG-I. PLoS Pathog 8:e1002809
Jehl, Stephanie P; Doling, Amy M; Giddings, Kara S et al. (2011) Antigen-specific CD8(+) T cells fail to respond to Shigella flexneri. Infect Immun 79:2021-30
van der Velden, Adrianus W M; Dougherty, Jeffrey T; Starnbach, Michael N (2008) Down-modulation of TCR expression by Salmonella enterica serovar Typhimurium. J Immunol 180:5569-74
Shaw, Christine A; Starnbach, Michael N (2008) Both CD4+ and CD8+ T cells respond to antigens fused to anthrax lethal toxin. Infect Immun 76:2603-11
Shaw, Christine A; Starnbach, Michael N (2008) Antigen delivered by anthrax lethal toxin induces the development of memory CD8+ T cells that can be rapidly boosted and display effector functions. Infect Immun 76:1214-22
D'Orazio, Sarah E F; Shaw, Christine A; Starnbach, Michael N (2006) H2-M3-restricted CD8+ T cells are not required for MHC class Ib-restricted immunity against Listeria monocytogenes. J Exp Med 203:383-91
Hang, Howard C; Loureiro, Joana; Spooner, Eric et al. (2006) Mechanism-based probe for the analysis of cathepsin cysteine proteases in living cells. ACS Chem Biol 1:713-23

Showing the most recent 10 out of 16 publications