Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI056068-02
Application #
6764004
Study Section
Special Emphasis Panel (ZRG1-BM-1 (01))
Program Officer
Schmitt, Clare K
Project Start
2003-07-01
Project End
2007-12-31
Budget Start
2004-01-01
Budget End
2004-12-31
Support Year
2
Fiscal Year
2004
Total Cost
$396,250
Indirect Cost
Name
Tufts University
Department
Biochemistry
Type
Schools of Medicine
DUNS #
039318308
City
Boston
State
MA
Country
United States
Zip Code
02111
Paczosa, Michelle K; Fisher, Michael L; Maldonado-Arocho, Francisco J et al. (2014) Yersinia pseudotuberculosis uses Ail and YadA to circumvent neutrophils by directing Yop translocation during lung infection. Cell Microbiol 16:247-68
Maldonado-Arocho, Francisco J; Green, Carlos; Fisher, Michael L et al. (2013) Adhesins and host serum factors drive Yop translocation by yersinia into professional phagocytes during animal infection. PLoS Pathog 9:e1003415
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Songsungthong, Warangkhana; Higgins, Mary C; Rolán, Hortensia G et al. (2010) ROS-inhibitory activity of YopE is required for full virulence of Yersinia in mice. Cell Microbiol 12:988-1001
Davis, Alison J; Díaz, Dennise A De Jesús; Mecsas, Joan (2010) A dominant-negative needle mutant blocks type III secretion of early but not late substrates in Yersinia. Mol Microbiol 76:236-59
Ren, Zhihong; Gay, Raina; Thomas, Adam et al. (2009) Effect of age on susceptibility to Salmonella Typhimurium infection in C57BL/6 mice. J Med Microbiol 58:1559-67
Balada-Llasat, Joan-Miquel; Panilaitis, Bruce; Kaplan, David et al. (2007) Oral inoculation with Type III secretion mutants of Yersinia pseudotuberculosis provides protection from oral, intraperitoneal, or intranasal challenge with virulent Yersinia. Vaccine 25:1526-33

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