We propose to strengthen our capacity to develop, implement, and evaluate data- and theory- driven HIV prevention interventions among men who have sex with men (MSM) in China. An estimated 650,000 persons were living with HIV in China in 2005 and transmission is shifting from injection drug users to populations at risk through sexual transmission. MSM in particular may be experiencing a rapid rise in HIV prevalence right now. In Beijing, HIV prevalence rose from less that 1% in 2004 to over 5% in 2006. HIV prevalence among MSM in Chongqing has already been measured over 15%. While grassroots community- and state- supported prevention programs for MSM are proliferating, they generally have not been guided by rigorous epidemiological data or by theory-based prevention approaches. We propose a four year program to progressively improve the theoretical foundation for HIV epidemiological surveys, prevention programs, and intervention research for MSM in China. The context of our effort will be three serial cross-sectional respondent-driven sampling (RDS) surveys, enhanced with specific training in behavioral research, formative research to adapt and validate detailed behavioral instruments for China, and assessment of the coverage and impact of existing prevention programs for MSM in Beijing and Chongqing. In addition to enhancing our capacity to conduct future large scale randomized controlled trials of HIV prevention interventions, the data collected through this proposal will have immediate applications in targeting the factors and behaviors driving HIV transmission among MSM in our country. By virtue of our team's leadership of locally and internationally funded programs for MSM, we are poised to rapidly incorporate findings into on-going efforts.

Public Health Relevance

As one of the first study conducted among men who have sex with men, the project will help understand HIV/AIDS epidemic among this population in China. It will also help identify high risk group, develop suitable survey tool to investigate risk behavior of men who have sex with men, as well as evaluate the effectiveness of ongoing programs in study areas.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Project (R01)
Project #
5R01AI078933-04
Application #
8139011
Study Section
Special Emphasis Panel (ZRG1-ICP2-B (50))
Program Officer
Chow, Grace C
Project Start
2008-09-25
Project End
2012-08-31
Budget Start
2011-09-01
Budget End
2012-08-31
Support Year
4
Fiscal Year
2011
Total Cost
$70,864
Indirect Cost
Name
National Center/AIDS/Std Control/Prevent
Department
Type
DUNS #
545274532
City
Beijing
State
Country
China
Zip Code
10220-6
Wang, Na; Wu, Guohui; Lu, Rongrong et al. (2016) Investigating HIV Infection and HIV Incidence Among Chinese Men Who Have Sex with Men with Recent Sexual Debut, Chongqing, China, 2011. AIDS Behav 20:2976-2982
Zhang, Heng; Lu, Hongyan; Pan, Stephen W et al. (2015) Correlates of unprotected anal intercourse: the influence of anal sex position among men who have sex with men in Beijing, china. Arch Sex Behav 44:375-87
Zhao, Yuejuan; Zhang, Li; Zhang, Heng et al. (2015) HIV testing and preventive services accessibility among men who have sex with men at high risk of HIV infection in Beijing, China. Medicine (Baltimore) 94:e534
Ruan, Yuhua; Wu, Guohui; Lu, Hongyan et al. (2014) Sexual partnerships with men and women among men who have sex with men in Beijing and Chongqing, China, 2010. AIDS Behav 18:180-8
Li, Xuefeng; Lu, Hongyan; Cox, Catherine et al. (2014) Changing the landscape of the HIV epidemic among MSM in China: results from three consecutive respondent-driven sampling surveys from 2009 to 2011. Biomed Res Int 2014:563517
Hu, Yifei; Lu, Hongyan; Raymond, H Fisher et al. (2014) Measures of condom and safer sex social norms and stigma towards HIV/AIDS among Beijing MSM. AIDS Behav 18:1068-74
Ma, Wei; Ding, Xianbin; Lu, Hongyan et al. (2013) HIV risk perception among men who have sex with men in two municipalities of China--implications for education and intervention. AIDS Care 25:385-9
Zhang, Lan; Xiao, Yan; Lu, Rongrong et al. (2013) Predictors of HIV testing among men who have sex with men in a large Chinese city. Sex Transm Dis 40:235-40
Lu, Hongyan; Han, Yang; He, Xiong et al. (2013) Alcohol use and HIV risk taking among Chinese MSM in Beijing. Drug Alcohol Depend 133:317-23
Zhou, Chao; Raymond, H Fisher; Ding, Xianbin et al. (2013) Anal sex role, circumcision status, and HIV infection among men who have sex with men in Chongqing, China. Arch Sex Behav 42:1275-83

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