Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis, Diabetes, Digestive and Kidney Diseases (NIADDK)
Type
Research Project (R01)
Project #
3R01AM014334-16S1
Application #
3150907
Study Section
Metabolism Study Section (MET)
Project Start
1975-05-01
Project End
1985-08-31
Budget Start
1985-05-01
Budget End
1985-08-31
Support Year
16
Fiscal Year
1985
Total Cost
Indirect Cost

  Institution

Name
University of Virginia
Department
Type
Schools of Medicine
DUNS #
001910777
City
Charlottesville
State
VA
Country
United States
Zip Code
22904

  Publications

Galasko, G T; Abe, S; Lilley, K et al. (1996) Circulating factors and insulin resistance. II. The action of the novel myo-inositol cyclic 1,2-inositol phosphate phosphoglycan insulin antagonist from human plasma in regulating pyruvate dehydrogenase phosphatase. J Clin Endocrinol Metab 81:1051-7
Paule, C R; Larner, J (1996) Characterization of a nucleotide stimulated aspartic proteinase in rat liver plasma membranes. J Basic Clin Physiol Pharmacol 7:121-36
Galasko, G T; Bao, Y; Broomfield, S J et al. (1995) Circulating factors and insulin resistance. I. A novel myoinositol 1,2-cyclic phosphate phosphoglycan insulin antagonist from human plasma is elevated in noninsulin-dependent diabetes mellitus. J Clin Endocrinol Metab 80:2419-29
Romero, G; Gamez, G; Huang, L C et al. (1990) Anti-inositolglycan antibodies selectively block some of the actions of insulin in intact BC3H1 cells. Proc Natl Acad Sci U S A 87:1476-80
Larner, J; Huang, L C; Suzuki, S et al. (1989) Insulin mediators and the control of pyruvate dehydrogenase complex. Ann N Y Acad Sci 573:297-305
Romero, G; Luttrell, L; Rogol, A et al. (1988) Phosphatidylinositol-glycan anchors of membrane proteins: potential precursors of insulin mediators. Science 240:509-11
Messina, J L; Hamlin, J; Larner, J (1987) Insulin-mimetic actions of wheat germ agglutinin and concanavalin A on specific mRNA levels. Arch Biochem Biophys 254:110-5
Malchoff, C D; Huang, L; Gillespie, N et al. (1987) A putative mediator of insulin action which inhibits adenylate cyclase and adenosine 3',5'-monophosphate-dependent protein kinase: partial purification from rat liver: site and kinetic mechanism of action. Endocrinology 120:1327-37
Leef, J W; Larner, J (1987) Insulin-mimetic effect of trypsin on the insulin receptor tyrosine kinase in intact adipocytes. J Biol Chem 262:14837-42
Suzuki, S; Toyota, T; Tamura, S et al. (1987) ATP-Mn2+ stimulates the generation of a putative mediator of insulin action. J Biol Chem 262:3199-204

Showing the most recent 10 out of 16 publications