Epstein-Barr Virus and Autoimmune Disease

Vaughan, John H.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
• Type: Research Project (R01)
• Project #: 5R01AR021175-13
• Application #: 3155159
• Study Section: General Medicine A Subcommittee 2 (GMA)
• Project Start: 1977-12-01
• Project End: 1990-06-30
• Budget Start: 1990-02-01
• Budget End: 1990-06-30
• Support Year: 13
• Fiscal Year: 1990

Institution

• Name: Scripps Research Institute
• City: San Diego
• State: CA
• Country: United States
• Zip Code: 92037

Publications

Handley, H H; Yu, J; Yu, D T et al. (1996) Autoantibodies to human heat shock protein (hsp)60 may be induced by Escherichia coli groEL. Clin Exp Immunol 103:429-35

Vaughan, J H; Nguyen, M D; Valbracht, J R et al. (1995) Epstein-Barr virus-induced autoimmune responses. II. Immunoglobulin G autoantibodies to mimicking and nonmimicking epitopes. Presence in autoimmune disease. J Clin Invest 95:1316-27

Vaughan, J H; Valbracht, J R; Nguyen, M D et al. (1995) Epstein-Barr virus-induced autoimmune responses. I. Immunoglobulin M autoantibodies to proteins mimicking and not mimicking Epstein-Barr virus nuclear antigen-1. J Clin Invest 95:1306-15

Handley, H H; Ngyuen, M D; Yu, D T et al. (1995) Purification of recombinant human Hsp60: use of a GroEL-free preparation to assess autoimmunity in rheumatoid arthritis. J Autoimmun 8:659-73

Zuraw, B L; Lotz, M (1990) Regulation of the hepatic synthesis of C1 inhibitor by the hepatocyte stimulating factors interleukin 6 and interferon gamma. J Biol Chem 265:12664-70

Kouri, T; Petersen, J; Rhodes, G et al. (1990) Antibodies to synthetic peptides from Epstein-Barr nuclear antigen-1 in sera of patients with early rheumatoid arthritis and in preillness sera. J Rheumatol 17:1442-9

Rhodes, G; Smith, R S; Rubin, R E et al. (1990) Identical IgM antibodies recognizing a glycine-alanine epitope are induced during acute infection with Epstein-Barr virus and cytomegalovirus. J Clin Lab Anal 4:456-64

Kouri, T; Crowley, J; Aho, K et al. (1990) Occurrence of two germline-related rheumatoid factor idiotypes in rheumatoid arthritis and in non-rheumatoid seropositive individuals. Clin Exp Immunol 82:250-6

Petersen, J; Rhodes, G; Roudier, J et al. (1990) Altered immune response to glycine-rich sequences of Epstein-Barr nuclear antigen-1 in patients with rheumatoid arthritis and systemic lupus erythematosus. Arthritis Rheum 33:993-1000

Vaughan, J H (1989) Infection and autoimmunity. Curr Opin Immunol 1:708-17