Crystallographic Studies of Troponin C

Sundaralingam, Muttaiya

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
• Type: Research Project (R01)
• Project #: 5R01AR034139-06
• Application #: 3156740
• Study Section: Biophysical Chemistry Study Section (BBCB)
• Project Start: 1984-08-01
• Project End: 1990-08-31
• Budget Start: 1990-03-01
• Budget End: 1990-08-31
• Support Year: 6
• Fiscal Year: 1990

Institution

• Name: University of Wisconsin Madison
• Type: Schools of Earth Sciences/Natur
• DUNS #: 161202122
• City: Madison
• State: WI
• Country: United States
• Zip Code: 53715

Publications

Sekharudu, C Y; Sundaralingam, M (1993) A model for the calmodulin-peptide complex based on the troponin C crystal packing and its similarity to the NMR structure of the calmodulin-myosin light chain kinase peptide complex. Protein Sci 2:620-5

Sundaralingam, M; Sekharudu, Y C (1989) Water-inserted alpha-helical segments implicate reverse turns as folding intermediates. Science 244:1333-7

Sekharudu, Y C; Sundaralingam, M (1988) A structure-function relationship for the calcium affinities of regulatory proteins containing 'EF-hand' pairs. Protein Eng 2:139-46

Satyshur, K A; Rao, S T; Pyzalska, D et al. (1988) Refined structure of chicken skeletal muscle troponin C in the two-calcium state at 2-A resolution. J Biol Chem 263:1628-47